Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesisOACSTPCD
Translesion DNA synthesis(TLS)can bypass DNA lesions caused by chemotherapeutic drugs,which usually result in drug resistance.Given its key role in mutagenesis and cell survival after DNA damage,inhibition of the TLS pathway …查看全部>>
Xiaolu Ma;Fei Yang;Ke Ma;Hongyan Shen;Junjie Han;Kai Wang;Yeran Yang;Jiawei Zhu;Ruiyuan An;Qilin Wang;Tie-Shan Tang;Bo Zhou;Hongwei Liu;Caixia Guo
College of Biomedical Engineering,Taiyuan University of Technology,Taiyuan 030024,China CAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,China State Key Laboratory of Membrane Biology,Institute of Zoology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaInstitute of Microbiology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaInstitute of Microbiology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaInstitute of Microbiology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaState Key Laboratory of Membrane Biology,Institute of Zoology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,China Beijing Institute for Stem Cell and Regenerative Medicine,Beijing 100101,China University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaInstitute of Microbiology,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,ChinaCAS Key Laboratory of Genomics and Precision Medicine,Beijing Institute of Genomics/China National Center for Bioinformation,University of Chinese Academy of Sciences,Chinese Academy of Sciences,Beijing 100101,China
化学工程
Ganoderma boninenseGanoboninketal CCisplatin chemotherapyTranslesion DNA synthesis
《Food Science and Human Wellness》 2024 (5)
P.2982-2992,11
supported by National Key Research and Development Program of China(2018YFA0108500)NSFC82341006,81673334,31970740,31801144,31800684 and 31701227Natural Science Foundation of Beijing(IS23071)Postdoctoral Research Foundation of China(2021M703206)Natural Science Foundation of Shanxi Province(202203021211155)the State Key Laboratory of Membrane Biology.