Saikosaponin D improves nonalcoholic fatty liver disease via gut microbiota-bile acid metabolism pathwayOACSTPCD
Non-alcoholic fatty liver disease(NAFLD)is the main cause of chronic liver disease worldwide.Bupleurum is widely used in the treatment of non-alcoholic fatty liver,and saikosaponin D(SSD)is one of the main active components o…查看全部>>
Lan Li;Shengye Yang;Xinyu Liang;Yameng Liu;Hualing Xu;Xiaozhen Guo;Cen Xie;Xiaojun Xu
State Key Laboratory of Natural Medicines,China Pharmaceutical University,Nanjing 210029,ChinaState Key Laboratory of Natural Medicines,China Pharmaceutical University,Nanjing 210029,China Guangdong Provincial People''s Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210029,ChinaState Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210029,ChinaState Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaSchool of Chinese Materia Medica,Nanjing University of Chinese Medicine,Nanjing 210029,China State Key Laboratory of Drug Research,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,ChinaState Key Laboratory of Natural Medicines,China Pharmaceutical University,Nanjing 210029,China Guangdong Provincial People''s Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China
轻工业
Saikosaponin D(SSD)Non-alcoholic fatty liver diseaseBile acidsGut microbiotaFarnesoid X receptor
《Food Science and Human Wellness》 2024 (5)
P.2703-2717,15
supported by National Natural Science Foundation of China (82222071, 82273990, 82104253)the opening project of State Key Laboratory of Natural Medicines (SKLNMKF202208)
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