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Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

Lifang Zhao Mingkai Zhang Qimeng Li Xuemin Wang Jie Lu Ying Han Yanning Cai

Neural Regeneration Research2025，Vol.20Issue(8)：P.2373-2381,9.

Neural Regeneration Research2025，Vol.20Issue(8)：P.2373-2381,9.DOI:10.4103/NRR.NRR-D-23-01983

Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases

Lifang Zhao ¹Mingkai Zhang ²Qimeng Li ¹Xuemin Wang ¹Jie Lu ³Ying Han ⁴Yanning Cai⁵

作者信息

1. Department of Clinical Biobank,Xuanwu Hospital,Capital Medical University,Beijing,China Beijing Geriatric Medical Research Center,Beijing,China
2. Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing,China
3. Department of Radiology and Nuclear Medicine,Xuanwu Hospital,Capital Medical University,Beijing,China Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics,Beijing,China Key Laboratory of Neurodegenerative diseases,Ministry of Education,Beijing,China
4. Department of Neurology,Xuanwu Hospital,Capital Medical University,Beijing,China School of Biomedical Engineering,Hainan University,Haikou,Hainan Province,China Center of Alzheimer’s Disease,Beijing Institute for Brain Disorders,Beijing,China National Clinical Research Center for Geriatric Diseases,Beijing,China Institute of Biomedical Engineering,Shenzhen Bay Laboratory,Gaoke Innovation Center,Shenzhen,Guangdong Province,China
5. Department of Clinical Biobank,Xuanwu Hospital,Capital Medical University,Beijing,China Beijing Geriatric Medical Research Center,Beijing,China Key Laboratory of Neurodegenerative diseases,Ministry of Education,Beijing,China Department of Neurobiology,Xuanwu Hospital,Capital Medical University,Beijing,China
折叠

摘要

关键词

Alzheimer’s disease/amyloid-β/diagnostic ability/glial fibrillary acidic protein/neurodegeneration/neurofilament light chain/plasma biomarkers/single molecule array/storage time/tau

分类

医药卫生

引用本文复制引用

Lifang Zhao,Mingkai Zhang,Qimeng Li,Xuemin Wang,Jie Lu,Ying Han,Yanning Cai..Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases[J].Neural Regeneration Research,2025,20(8):P.2373-2381,9.

基金项目

supported by the National Key Research&Development Program of China,Nos.2021YFC2501205(to YC),2022YFC24069004(to JL) （to YC）

the STI2030-Major Project,Nos.2021ZD0201101(to YC),2022ZD0211800(to YH) （to YC）

the National Natural Science Foundation of China(Major International Joint Research Project),No.82020108013(to YH) （Major International Joint Research Project）

the Sino-German Center for Research Promotion,No.M-0759(to YH) （to YH）

a grant from Beijing Municipal Science&Technology Commission(Beijing Brain Initiative),No.Z201100005520018(to JL)。（Beijing Brain Initiative）

Neural Regeneration Research

ISSN：1673-5374

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