中医康复2024，Vol.1Issue(7)：43-46,4.DOI:10.19787/j.issn.2097-3128.2024.07.009
鼻咽癌放疗后患者吞咽困难发生的相关影响因素及其干预措施分析
Influencing Factors and Intervention Measures for Dysphagia in Nasopharyngeal Carcinoma Patients after Radiotherapy
摘要
Abstract
Objective:To explore the influencing factors and intervention measures for dysphagia in nasopharyngeal carcinoma patients after radio-therapy.Methods:A convenience sampling method was used to select 400 nasopharyngeal carcinoma patients who underwent radiotherapy in our hospital from March 2020 to March 2023 as the research subjects.The incidence of dysphagia and related influencing factors in nasopharyngeal car-cinoma patients after radiotherapy were investigated.Results:The incidence of dysphagia in nasopharyngeal carcinoma patients after radiotherapy was 65.00％(260/400);Univariate analysis showed that age,clinical TNM staging of tumors,radiation dose,radiation stomatitis,and radiation der-matitis were associated with difficulty swallowing in nasopharyngeal carcinoma patients after radiotherapy(P＜0.05);Education level,marital status,BMI before radiotherapy,duration of radiotherapy,gender,smoking,comorbidities with underlying diseases,concurrent chemotherapy,and alcohol consumption were not associated with dysphagia in nasopharyngeal carcinoma patients after radiotherapy(P＞0.05).Logistic regression analysis showed that age≥60 years(B=0.934,OR=2.545,95％CI=1.652-3.922),tumor clinical TNM stage Ⅲ-Ⅳ(B=1.142,OR=3.132,95％CI=2.06-4.888),radiation dose＞72Gy(B=0.703,OR=2.020,95％CI=1.312-3.111),radiation stomatitis(B=1.593,OR=4.920,95％CI=3.049-7.939)Radiation dermati-tis(B=1.529,OR=4.612,95％CI=2.956-7.197)is a high-risk factor for dysphagia in nasopharyngeal carcinoma patients after radiotherapy(P＜0.05).Conclusion:The incidence of dysphagia in nasopharyngeal carcinoma patients after radiotherapy is relatively high,which is influenced by various factors such as age,tumor clinical TNM staging,radiation dose,radiation stomatitis,and radiation dermatitis.Developing intervention measures based on these factors may reduce or avoid the occurrence of dysphagia in patients.关键词
鼻咽癌/吞咽困难/放射疗法/放射性口腔炎/放射性皮炎/影响因素/干预措施Key words
nasopharyngeal cancer/difficulty swallowing/radiotherapy/radiation stomatitis/radiation dermatitis/influencing factors/intervention measures分类
医药卫生引用本文复制引用
高薇薇,董晓鸣,李舰波,周静,王治华..鼻咽癌放疗后患者吞咽困难发生的相关影响因素及其干预措施分析[J].中医康复,2024,1(7):43-46,4.基金项目
浙江省教育厅科研计划项目(Y202045388) （Y202045388）
