国际神经病学神经外科学杂志2024,Vol.51Issue(4):60-64,5.DOI:10.16636/j.cnki.jinn.1673-2642.2024.04.010
心率变异性与脑小血管病相关研究进展
Research advances in the association between heart rate variability and cerebral small vessel disease
摘要
Abstract
Cerebral small vessel disease(CSVD)is a type of vascular disease that affects the whole brain,and it is often associated with high prevalence rate and disease burden.At present,the etiology and treatment of CSVD remain unclear.As a noninvasive marker,heart rate variability(HRV)is used for the quantitative assessment of autonomic nervous function,and it mirrors the equilibrium of the nervous system and is closely associated with blood pressure regulation,inflammatory response,and metabolic processes.Previous studies have shown that the reduction in HRV may be associated with the development and progression of CSVD,although there is a lack of consistent findings.This article reviews the studies on the association of HRV with the imaging and clinical manifestations of CSVD and further explores the possible pathogenic mechanism of CSVD,in order to provide new directions for the prevention and treatment of CSVD.关键词
心率变异性/脑小血管病/自主神经功能Key words
heart rate variability/cerebral small vessel disease/autonomic nervous system function分类
医药卫生引用本文复制引用
郑兰,易芳,谷文萍..心率变异性与脑小血管病相关研究进展[J].国际神经病学神经外科学杂志,2024,51(4):60-64,5.基金项目
湖南省重点研发项目(2023SK2019) (2023SK2019)
国家自然科学基金(8237053040) (8237053040)