军事医学2024,Vol.48Issue(8):636-640,5.DOI:10.7644/j.issn.1674-9960.2024.08.013
黄热病毒保护性抗体研究进展
Research progress in protective antibodies against yellow fever virus
摘要
Abstract
Yellow fever virus(YFV)is one of the most important mosquito-borne flaviviruses in the world,causing about 200,000 infections and 30,000 deaths each year,with serious impacts on human health and economic development.Currently,there are no approved specific anti-viral drugs for YFV infection.On the other hand,antibody drugs are safe,highly targeted and effective,making them one of the most effective means of prevention and treatment of viral infectious diseases.This review summarizes the characteristics of YFV and the recent advances in the development of protective antibodies against YFV,and predict the priorities of future research and development of protective antibodies,which may offer a new line of thought for subsequent development of yellow fever virus-specific drugs.关键词
黄热病毒/包膜蛋白/中和抗体Key words
yellow fever virus/envelope protein/neutralizing antibody分类
医药卫生引用本文复制引用
索星星,迟航,邓永强,韩晓东..黄热病毒保护性抗体研究进展[J].军事医学,2024,48(8):636-640,5.基金项目
内蒙古自治区自然科学基金面上项目(2022SHZR1769) (2022SHZR1769)