日用化学工业（中英文）2024，Vol.54Issue(9)：1015-1022,8.DOI:10.3969/j.issn.2097-2806.2024.09.001
二氧化硅包载对维生素C稳定性提高的研究
Study on the silicon dioxide encapsulation for the enhancement of vitamin C stability
摘要
Abstract
To improve the stability of vitamin C(Vc)in cosmetics,Vc was coated with silica dioxide(Vc@SiO2),modified by silane(Vc@s-SiO2)and dispersed in decanoyl/octanoyl-glycerides(GTCC)oil phase system.The experimental results show that the encapsulation rate and drug loading rate are 68.2%and 13.6%,respectively,when Vc is encapsulated into silica dioxide.After modification,the surface of Vc@s-SiO2 is hydrophobic and the contact angle increases from 33.6° to 130.7°.When Vc is maintained at 50℃or exposed to ultraviolet light,Vc@s-SiO2 exhibits an increase in antioxidant activity by 11.4 times and 27.7 times,respectively,compared to free Vc.This study reveals that silica dioxide coated Vc and dispersed in GTCC can isolate the adverse factors such as water oxygen,reduce the activity loss and improve the stability of Vc.关键词
生物活性物/二氧化硅/维生素C/硅烷改性/稳定性Key words
bioactive substance/silicon dioxide/vitamin C/silane modification/stability分类
化学化工引用本文复制引用
石美玲,陈娟博,李皓,黄员琴,张启清,曾飒,孟涛..二氧化硅包载对维生素C稳定性提高的研究[J].日用化学工业（中英文）,2024,54(9):1015-1022,8.基金项目
国家自然科学基金资助项目(22378336,22204130) （22378336,22204130）
四川省科技厅重点研发项目(2020YFG0092,2021YFN0129) （2020YFG0092,2021YFN0129）
企业联合项目(R111322H01008) （R111322H01008）
