神经病学与神经康复学杂志2024，Vol.20Issue(2)：47-57,11.DOI:10.12022/jnnr.2021-0025
肌萎缩侧索硬化病因与中西医治疗新进展
New progress in the etiology and treatment of amyotrophic lateral sclerosis with traditional Chinese and Western medicine
摘要
Abstract
Amyotrophic lateral sclerosis(ALS)is a chronic progressive neurodegenerative disease with no effective treatment The etiology of ALS is unknown but it is related to many factors such as genetics,diet,environment,and lifestyle habits.The pathogenesis of ALS includes glutamate excitatory toxicity,oxidative stress,mitochondrial dysfunction,and axon transport disruption.Currently,the approved ALS treatment drugs include Riluzole,Edaravone,Dextromethorphan/Quinidine and Tofersen injection.There are many drugs in clinical trails,but effective treatment options are still limited.This review summarizes the etiology and pathogenesis of ALS,and summarizes in detail the traditional Chinese and Western medicine treatment methods for ALS,which has great practicability in clinical practice.关键词
肌萎缩侧索硬化/病因/发病机制/中西医结合/治疗进展Key words
Amyotrophic lateral sclerosis/Etiology/Pathogenesis/Integrated Traditional Chinese and Western Medicine/Treatment progress引用本文复制引用
VORATUNYAKITT Napattharin,SAEREETAVEEKUN Natkitta,韩小敬,李睿,张海涵,王呈蕙,潘卫东..肌萎缩侧索硬化病因与中西医治疗新进展[J].神经病学与神经康复学杂志,2024,20(2):47-57,11.基金项目
上海市浦东新区卫生健康委员会卫生行业专项(PW2022E-03)Shanghai Pudong New Area Health Commission Industry Special Project(PW2022E-03) （PW2022E-03）
