临床医学工程2024，Vol.31Issue(9)：1113-1114,2.DOI:10.3969/j.issn.1674-4659.2024.09.1113
不同剂量瑞马唑仑在髋关节置换术中的镇静效果比较研究
Comparative Study on Sedation Effect of Different Doses of Remimazolam during Hip Arthroplasty
徐惠平 1余晓磊 1许倩1
作者信息
- 1. 灵宝市中医院手术麻醉科,河南三门峡 472500
- 折叠
摘要
Abstract
Objective To xompare the sedation effect of different doses of remimazolam during hip arthroplasty.Methods 72 patients undergoing hip arthroplasty in our hospital were selected and randomly divided into group A and group B,with 36 cases in each group.Both groups were given combined spinal epidural anesthesia.Group A was given continuous infusion of 3 μg kg-1·min-1 of remimazolam,and group B was given continuous infusion of 4 μg·kg1·min1 of remimazolam.The perioperative indicators,sedation effect and adverse reactions were compared between the two groups.Results The eye opening time,extubation time and orientation recovery time of group A were significantly shorter than those of group B(P＜0.05).5 min,15 min,30 min and 60 min after sedation,the BIS values of the two groups were significantly lower than those before block and after plane fixation(P＜0.05).15 min after sedation,the BIS value of group A was significantly higher than that of group B(P＜0.05).The incidence of adverse reactions of group A was significantly lower than that of group B(P＜0.05).Conclusions Compared with intraoperative infusion of 4 μg·kg-1·min-1,infusion of 3 μg·kg1·min-1 of remimazolam has good sedation effect,short recovery time and higher safety.关键词
髋关节置换术/瑞马唑仑/不同剂量/镇静效果/安全性Key words
Hip arthroplasty/Remimazolam/Different doses/Sedation effect/Safety分类
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徐惠平,余晓磊,许倩..不同剂量瑞马唑仑在髋关节置换术中的镇静效果比较研究[J].临床医学工程,2024,31(9):1113-1114,2.
