儿童脓毒性休克液体复苏的最佳实践OA北大核心CSTPCD
Best practice of fluid resuscitation for septic shock in children
脓毒性休克属于儿童急危重症,也是全世界儿童死亡的主要原因之一.脓毒性休克的病理生理机制较复杂,液体复苏是脓毒性休克管理的基石.合理的复苏治疗对病情的改善至关重要.文章通过引入脓毒性休克液体复苏的抢救、优化、稳定和降级(salvage,optimization,stabilization and de-escalation,SOSD)理念来正确识别及理解儿童脓毒性休克液体复苏的4个时期过渡及变化,并对选择何种复苏液体、液体复苏总量、液体复苏速率等复苏策略方面进行阐述,以期为儿童脓毒性休克的液体复苏临床实践提供参考.
Septic shock belongs to children's critical illness,and it is also one of the main causes of children's death all over the world.The pathophysiologic mechanisms of septic shock are complex,and fluid resuscitation is the cornerstone of the managemnt of septic shock.Reasonable resuscitation treatment is crucial to the improvement of the condition.We introduce the concept of SOSD to correctly identify and understand the transition and changes of the four periods of fluid resuscitation in children with septic shock,and to elaborate on resuscitation strategies such as what kind of resuscitation fluids to choose,the total amount of fluid to be resuscitated,and the fluid resuscitation rate,in order to provide references for clinical practice of fluid resuscitation in children with septic shock.
陈锡龙;周冰莹;张太宁;王卫凯
甘肃省妇幼保健院(甘肃省中心医院)儿童急救中心二部,甘肃 兰州 730050
临床医学
儿童脓毒性休克液体复苏复苏理念策略
childseptic shockfluid resuscitationresuscita-tion conceptstrategy
《中国实用儿科杂志》 2024 (009)
674-679 / 6
甘肃省省级科技计划(科技重大专项)项目(22ZD6FA034);兰州市人才创新创业项目(2021-RC-139)
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