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肝动脉灌注化疗在肝细胞癌治疗中研究进展

张炜浩 高炜 司同国 邢文阁 于海鹏 陈璐

中国实用外科杂志2024,Vol.44Issue(8):953-958,6.
中国实用外科杂志2024,Vol.44Issue(8):953-958,6.DOI:10.19538/j.cjps.issn1005-2208.2024.08.23

肝动脉灌注化疗在肝细胞癌治疗中研究进展

Research progress of hepatic arterial Infusion chemotherapy in the treatment of hepatocellular carcinoma

张炜浩 1高炜 1司同国 1邢文阁 1于海鹏 1陈璐2

作者信息

  • 1. 天津医科大学肿瘤医院 国家肿瘤临床医学研究中心天津市恶性肿瘤临床医学研究中心 天津市消化系统肿瘤重点实验室药物成药性评价与系统转化重点实验室介入治疗科,天津 300060
  • 2. 天津医科大学肿瘤医院 国家肿瘤临床医学研究中心天津市恶性肿瘤临床医学研究中心 天津市消化系统肿瘤重点实验室药物成药性评价与系统转化重点实验室肝胆肿瘤科,天津 300060
  • 折叠

摘要

Abstract

Hepatocellular carcinoma(HCC)is one of the most common malignant tumors,which seriously threatens the health and quality of life of Chinese people.Systematic therapy represented by targeted and immunotherapy is the standard treatment for advanced HCC,but the overall effective rate is not high.Hepatic arterial infusion chemotherapy(HAIC)can effectively control intrahepatic tumors,with the advantages of minimally invasiveness and good safety.Systemic therapy combined with HAIC can effectively improve the objective remission rate and disease control rate,and improve the quality of life.Currently,there are reports on the positive application of HAIC in the downgrading before surgery,adjuvant treatment after surgery,and comprehensive treatment.However,how to screen out the advantageous population at the initial diagnosis of patients and achieve individualized medication according to the characteristics of patients'condition still needs to be further explored.

关键词

肝细胞癌/肝动脉灌注化疗/分子靶向治疗/免疫治疗

Key words

hepatocellular carcinoma/hepatic artery infusion chemotherapy/molecular targeted therapy/immunotherapy

分类

医药卫生

引用本文复制引用

张炜浩,高炜,司同国,邢文阁,于海鹏,陈璐..肝动脉灌注化疗在肝细胞癌治疗中研究进展[J].中国实用外科杂志,2024,44(8):953-958,6.

基金项目

天津市教委科研计划项目(No.2023KJ090) (No.2023KJ090)

中国实用外科杂志

OA北大核心CSTPCD

1005-2208

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