调神方针刺改善慢性失眠患者入睡潜伏期及过度觉醒的临床研究OACSTPCD
Clinical Study of Spirit-Regulating Acupuncture Improving Sleep Latency and Hyperarousal of Patients with CID
目的:观察调神方针刺对改善慢性失眠患者入睡潜伏期和过度觉醒状态的临床疗效.方法:将100例慢性失眠患者随机分为治疗组和对照组,各50例.治疗组予调神方针刺得气,穴取百会、神庭、四神聪、本神、神门、内关和三阴交;对照组取治疗失眠无效的经穴浅刺.每次均留针30 min,3次/周,治疗4周,给予相同的睡眠卫生指导.比较两组患者治疗前后及治疗结束后第8周随访期睡眠日记记录的入睡潜伏期、匹兹堡睡眠质量指数(PSQI)评分及过度觉醒量表(HAS)评分变化,并分析治疗后入睡潜伏期改善情况与过度觉醒水平变化的相关性.结果:治疗4周后,治疗组入睡潜伏期较前减短,差异具有统计学意义(P<0.01),随访期,两组入睡潜伏期均较前减短,差异具有统计学意义(P<0.05);治疗后及随访期,两组PSQI评分及HAS评分均较治疗前降低,差异具有统计学意义(P<0.05).治疗4周后,治疗组入睡潜伏期低于对照组,差异具有统计学意义(P<0.01),治疗后及随访期PSQI评分及HAS评分均较对照组明显下降,差异具有统计学意义(P<0.05).入睡潜伏期减少与过度觉醒水平降低呈正相关.结论:调神方针刺能有效减短慢性失眠患者的入睡潜伏期,提高睡眠质量,而降低过度觉醒水平是减少睡眠潜伏期的潜在机制.
Objective:To observe the clinical effectiveness of spirit-regulating acupuncture in improving sleep latency and hyperarousal among patients suffering from chronic insomnia disorder(CID).Methods:100 CID patients were randomly assigned into the treatment group and the control group,with 50 patients in each group.The treatment group was treated with spirit-regulating acupuncture,and the acupoints chosen were Baihui(DU20),Shenting(DU24),Sishencong(EX-HN4),Benshen(GB13),Shenmen(HT7),Neiguan(PC6)and Sanyinjiao(SP6).The control group was treated with shallow needling ineffective points for insomnia.The needling was 3 times per week for four weeks,with 30 min needle retention each time.The patients in both groups were provided the same sleep hygiene guidance.Sleep latency,Pittsburgh Sleep Quality Index(PSQI)score and Hyperarousal scale(HAS)score in the sleep diary were evaluated and compared between the two groups before the treatment,after the treatment and 8 weeks after the treatment.The correlation was analyzed between the improvement of sleep latency and the changes of hyperarousal level.Results:The sleep latency was shorter after 4 weeks of the treatment compared with that before the treatment in the two groups(P<0.01);the sleep latency was shorter during the follow-up compared with that before the treatment in the two group(P<0.05).Both the PSQI score and HAS score were significantly reduced in the two groups after the treatment and during the follow-up(P<0.05).The sleep latency was shorter in the treatment group than that in the control group after 4 weeks of the treatment(P<0.01).The PSQI score and the HAS score were significantly decreased in the treatment group than those in the control group after the treatment(P<0.05).The reduction of sleep latency is positively correlated with the decrease of the hyperarousal level.Conclusion:Spirit-regulating acupuncture can effectively shorten sleep latency,improve sleep quality and reduce hyperarousal,which is the potential mechanism of improving sleep.
朱丽颖;陈坤;姜同菲;陈昭伊;王桂玲;郭静
北京中医药大学,北京 100029||首都医科大学附属北京中医医院针灸中心针灸神经调控北京市重点实验室,北京 100010首都医科大学附属北京中医医院针灸中心针灸神经调控北京市重点实验室,北京 100010
中医学
慢性失眠调神方针刺入睡潜伏期过度觉醒临床试验
Chronic insomnia disorderSpirit-regulating prescriptionAcupunctureSleep latencyHyperarousalClinical trial
《针灸临床杂志》 2024 (009)
10-15 / 6
国家自然科学基金面上项目,编号:81774391;北京市自然科学基金面上项目,编号:7212170;北京市医院管理中心重点医学专业项目,编号:ZYLX202140.
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