针灸临床杂志2024，Vol.40Issue(9)：107-112,6.DOI:10.19917/j.cnki.1005-0779.024184
针康法调节细胞凋亡信号通路改善缺血性脑卒中研究进展
Research Progress on Acupuncture-Rehabilitation Therapy Improving Ischemic Stroke by Regulating Apoptosis Signaling Pathway
摘要
Abstract
Ischemic stroke is a common cardiovascular and cerebrovascular disease caused by obstruction of cerebral arteries and triggered by thrombosis or embolism or atherosclerosis.Acupuncture-rehabilitation therapy combines acupuncture and rehabilitation,where rehabilitation training is conducted during the retention of acupuncture needles.Neuron death caused by cerebral ischemia determines the mortality and disability rates of stroke.Apoptosis is a significant form of cell death following ischemic brain injury.Acupuncture-rehabilitation therapy can regulate apoptosis through intrinsic pathways,extrinsic pathways,the Notch signaling apoptosis pathway and the p53-mediated apoptosis pathway to reduce cell apoptosis and improve ischemic stroke.This study reviews how acupuncture-rehabilitation therapy improves ischemic stroke by regulating apoptotic signaling pathways,highlighting its therapeutic advantages.The aim is to provide theoretical support for the clinical application of acupuncture-rehabilitation therapy in treating ischemic stroke.关键词
缺血性脑卒中/针康法/细胞凋亡/自噬/铁死亡/焦亡Key words
Ischemic stroke/Acupuncture-rehabilitation therapy/Apoptosis/Autophagy/Ferroptosis/Necroptosis分类
医药卫生引用本文复制引用
李秀琼,唐强,赵婷婷,姜桐桐,穆姿辰,李宏玉..针康法调节细胞凋亡信号通路改善缺血性脑卒中研究进展[J].针灸临床杂志,2024,40(9):107-112,6.基金项目
黑龙江省自然科学基金重点项目,编号:ZD2019H007. （）
