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感冒清热颗粒致中毒性表皮坏死松解症

李慧芳 张爱武

疾病监测与控制2024,Vol.20Issue(3):173-175,3.
疾病监测与控制2024,Vol.20Issue(3):173-175,3.DOI:10.19891/j.issn1673-9388.(2024)03-0173-03

感冒清热颗粒致中毒性表皮坏死松解症

TOXIC EPIDERMAL NECROLYSIS INDUCED BY GANMAOQINGRE GRANULES

李慧芳 1张爱武1

作者信息

  • 1. 内蒙古医科大学附属医院 药剂部,内蒙古 呼和浩特 010050
  • 折叠

摘要

Abstract

A 28-year-old man with fever,dizziness,headache took Ganmaoqingre Granules 12 g twice daily.Three days later,he had dense miliary red rashes on his abdomen and extremities,accompanied by skin pruritus.Ganmaoqingre Granules was stopped and symptomatic treatment was given.Two days later,the patient developed red rashes all over the body rapidly.The edematous erythematous skin linked into pieces.The vesicles were visible on the surface.Meanwhile,skin and mucosal erosion appeared on his mouth,back and waist,accompanied by high fever and conjunctival congestion.On day 4 of treatment,Dense ves-icles and bullae occurred on his trunk and extremities,accompanied by pain,BSA>30%.Ganmaoqingre Granules-induced toxic epidermal necrolysis was diagnosed.He was treated with methylprednisolone,human immunoglobulin,calcium supplement with vitamin D chewable tablets,calcitriol soft capsules,omeprazole Magnesium enteric-coated tablets,foscarnet sodium,et al.His rashes gradually subsided.Fifteen days later,the drug eruptions were cured clinically.

关键词

感冒清热颗粒/表皮坏死松解症/中毒性

Key words

Ganmaoqingre Granules/epidermal necrdysis/toxic

分类

医药卫生

引用本文复制引用

李慧芳,张爱武..感冒清热颗粒致中毒性表皮坏死松解症[J].疾病监测与控制,2024,20(3):173-175,3.

基金项目

内蒙古医科大学青年培育项目(YKD2021QN013) (YKD2021QN013)

疾病监测与控制

1673-9388

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