四川大学学报（自然科学版）2024，Vol.61Issue(5)：213-222,10.DOI:10.19907/j.0490-6756.2024.056001
饥饿胁迫下罗非鱼下丘脑转录组研究
Transcriptomic studies on the hypothalamus of Nile tilapia(Oreochromis niloticus)under starvation stress
摘要
Abstract
Appetite regulation in fish exhibits species-specific difference.To analyze the appetite regulation mechanism of Nile tilapia(Oreochromis niloticus),this study employed RNA-Seq to analyze the transcrip-tome of the hypothalamus under short-term(3 days)and long-term(6 days)starvation stress.The multiple differentially expressed genes were isolated and further subjected to the KEGG analysis,GO analysis and pro-tein interaction analysis which supported that the melanocortin members play a key role in appetite regulation.In addition,the multiple hypothalamic regulatory factors including oxytocin(OX),galanin(GAL)etc.,were confirmed to be involved in appetite regulation.These results provide a preliminary understanding of the differential gene expression profile under starvation stress in tilapia.关键词
罗非鱼/饥饿胁迫/禁食/下丘脑/转录组Key words
Nile tilapia/Starvation stress/Fasting/Hypothalamus/Transcriptome分类
生物科学引用本文复制引用
刘天强,孙才云,王亚军..饥饿胁迫下罗非鱼下丘脑转录组研究[J].四川大学学报（自然科学版）,2024,61(5):213-222,10.基金项目
国家自然科学基金(32072706) （32072706）
四川大学-通威农业发展有限公司联合研发项目(TW-AH20130613) （TW-AH20130613）
