肿瘤预防与治疗2024，Vol.37Issue(9)：775-780,6.DOI:10.3969/j.issn.1674-0904.2024.09.006
术前CT结合NLR、PLR、CAR对cN0期胃癌患者术后淋巴结转移的预测价值
Predictive Value of Preoperative CT Combined with NLR,PLR and CAR for Postoperative Lymph Node Metastasis in Patients with cN0 Gastric Cancer
王思琦 1丁毅 1李曦 2雷智鑫1
作者信息
- 1. 643000 四川自贡,自贡市第四人民医院放射科
- 2. 643000 四川自贡,自贡市第四人民医院普外一科
- 折叠
摘要
Abstract
Objective:To explore the predictive value of preoperative CT combined with preoperative systemic inflamma-tory markers such as neutrophil to lymphocyte ratio(NLR),platelet to lymphocyte ratio(PLR)and C-reactive protein to al-bumin ratio(CAR)for postoperative lymph node metastasis in patients with cN0 gastric cancer.Methods:We retrospective-ly collected 210 cases of cN0 stage gastric cancer by preoperative CT diagnosis in our hospital from January 2021 to December 2023 as subjects.The clinical data and preoperative systemic inflammatory markers were collected.All patients underwent radical treatment for gastric cancer,and were assigned to the non-lymph node metastasis group(pN0)and the lymph node metastasis group(pN+)according to postoperative pathology.The differences in NLR,PLR and CAR were compared be-tween two groups,and the logistic regression model was used to screen the independent risk factors of lymph node metastasis in patients with cN0 gastric cancer.Results:Among the 210 cN0 gastric cancer patients,there were 107(50.95％)pN0 cases and 103(49.05％)pN+cases diagnosed by postopera-tive pathology.The overall levels of preoperative neutrophil count,platelet count,C-reactive protein,NLR and CAR in the pN+group were significantly higher than those in the pN0 group,and the differences were statistically significant(all P＜0.05).Univariate and multivariate logistic regression analyses showed that tumor maximum diameter ≥ 3.0 cm(OR=2.175),pT stage T3-T4(OR=2.201),NLR ≥2.19(OR=1.922)and CAR≥0.12(OR=3.631)were independent risk factors for postoperative lymph node metastasis in cNO stage gastric cancer patients,and the differences were statistically significant(all P＜0.05).Conclusion:Preoperative high NLR and CAR levels are independent risk factors for postoperative lymph node metastasis in cN0 stage gastric cancer patients diagnosed by preoperative CT.关键词
胃癌/计算机断层扫描/中性粒细胞和淋巴细胞比值/血小板和淋巴细胞比值/C反应蛋白和白蛋白比值/淋巴结转移Key words
Gastric cancer/CT/Neutrophil to lymphocyte ratio/Platelet to lymphocyte ratio/C-reactive protein to albu-min ratio/Lymph node metastasis分类
医药卫生引用本文复制引用
王思琦,丁毅,李曦,雷智鑫..术前CT结合NLR、PLR、CAR对cN0期胃癌患者术后淋巴结转移的预测价值[J].肿瘤预防与治疗,2024,37(9):775-780,6.
