护理研究2024，Vol.38Issue(19)：3403-3409,7.DOI:10.12102/j.issn.1009-6493.2024.19.004
冠心病病人PCI术后1年出血危险因素的模型构建和验证
Construction and validation of risk factors model related to hemorrhage in patients with coronary heart disease after PCI 1 year
摘要
Abstract
Objective:Based on LASSO-Logistic regression analysis of hemorrhage related factors in patients with coronary atherosclerotic heart disease(CHD)1 year after percutaneous coronary intervention(PCI),and to establish a Nomogram prediction model for timely and effective clinical intervention.Methods:226 patients with coronary heart disease who underwent PCI in our hospital from January to December 2021 were selected as the study objects,and were divided into hemorrhage group and non-hemorrhage group according to whether they had hemorrhage one year after PCI.LASSO-Logistic regression was used to screen the risk factors of hemorrhage 1 year after PCI,and further construct a Nomogram prediction model.Receiver operating characteristic(ROC)curve and calibration curve were used to verify the value of Nomogram prediction model.Results:One year after PCI,the incidence of hemorrhage in 226 patients with coronary heart disease was 11.95% .Age≥60 years old,gastrointestinal history,chronic renal insufficiency,use of vessel closure,balloon dilation times,PARIS score,precision-DAPT score were the risk factors for bleeding 1 year after PCI(P<0.05).The Nomogram prediction model predicted the AUC of hemorrhage at 1 year after PCI to be 0.959.Conclusion:Age≥60 years,history of digestive tract,chronic renal insufficiency,use of vessel closure,balloon dilation times,PARIS score and precision-DAPT score are risk factors for hemorrhage 1 year after PCI in patients with coronary heart disease.The establishment of a Nomogram prediction model based on LASSO-Logistic regression analysis has a certain value in predicting hemorrhage 1 year after PCI.Clinical screening and strict observation of high-risk groups should be carried out,and reasonable treatment measures should be formulated to reduce the risk of hemorrhage.关键词
冠心病/经皮冠状动脉介入术/LASSO-Logistic回归/出血/Nomogram模型/危险因素/预测Key words
coronary atherosclerotic heart disease/percutaneous coronary intervention,PCI/LASSO-Logistic regression/bleeding/Nomogram model/risk factors/forecast引用本文复制引用
宋利华,付继京,王俊伟..冠心病病人PCI术后1年出血危险因素的模型构建和验证[J].护理研究,2024,38(19):3403-3409,7.基金项目
河北省2021年度医学科学研究课题计划项目,编号:20210723 （）
