摘要
Abstract
Objective To analyze the pathogen distribution and drug resistance of bacterial pneumonia in infants.Methods A total of 102 infants with bacterial pneumonia admitted to Zibo Maternal and Child Health Hospital from January to December 2023 were selected as the study objects.Sputum aspiration was collected for bacterial culture,and drug susceptibility test was conducted to analyze the pathogenic distribution characteristics and drug resistance of the infants.Results Among the included infants,60 cases(58.82%)were infected with Gram-negative bacteria,25 strains of Klebsiella pneumoniae and 15 strains of Escherichia coli were detected.Forty-two cases(41.18%)were infected with Gram-positive bacteria,13 strains of Streptococcus pneumoniae and 18 strains of Staphylococcus aureus were detected.The resistance rate of Klebsiella pneumoniae to Ampicillin and Cefazolin was higher,and the resistance rate to Meropenem was lower.The resistance rate of Escherichia coli to Ampicillin was higher,but the resistance rate to Meropenem,Ceftazidime,and Cefoxitin was lower.The resistance rate of Pseudomonas aeruginosa to Ampicillin,Ampicillin/Sulbactam,Cefazolin,Cefuroxime,and Cefoxitin was higher,and the resistance rate to Meropenem,Ceftriaxone,and Ceftazidime was lower.The resistance rate of Streptococcus pneumoniae to Clindamycin was higher,and the resistance rate to Vancomycin and Oxacillin was lower.The resistance rate of Staphylococcus aureus to Clindamycin was higher,and the resistance rate to Vancomycin was lower.Conclusion The etiology of infantile bacterial pneumonia is diverse,with Klebsiella pneumoniae,Escherichia coli and Staphylococcus aureus being the most common,and the resistance rate to a variety of antibiotics is high.Clinical management of medication should be strengthened,and treatment should be guided by the results of bacterial culture and drug sensitivity test.关键词
细菌性肺炎/病原学/革兰氏阴性菌/革兰氏阳性菌/耐药性Key words
Bacterial pneumonia/Etiology/Gram-negative bacteria/Gram-positive bacteria/Drug resistance分类
医药卫生