现代畜牧科技Issue(9)：31-34,4.DOI:10.19369/j.cnki.2095-9737.2024.09.009
初乳对新生腹泻肉用犊牛免疫功能和直肠粪便菌群的影响
Effects of Colostrum on Immune Functions and Rectal Fecal Flora of Newborn Diarrhea Calves
摘要
Abstract
This experiment was conducted to investigate the effects of colostrum on behavior,body weight,serum immune factors,peripheral blood lymphocyte subsets and rectal fecal microbial community of neonatal diarrhea beef calves.5 healthy Simmental calves and 20 diarrhea calves born 1 week old near Tongliao City were selected and randomly divided into 4 groups.Each group was fed with 0,2,4 and 6 L of colostrum per day,and the control group was fed with 2 L of colostrum per day for 7 days.The results show that:compared with the other three text group,the colostrum medium-dose group reduced the levels of TNF-α,IL-1β,IL-6,INF-γ,MPO and CD8+T,while increasing the levels of IL-2,TGFβ2,CD4+T,CD3+T and CD19+B,as well as increasing the body temperature,body weight and reducing the time of fecal excretion,indicating that colostrum has anti-inflammatory effects.In the rectum,colostrum decreased the number of E.coli and increased the number of Bacillus fragilis,Bifidobacterium and Lactobacillus.In summary,the study found that feeding 4 L colostrum can improve the anti-inflammatory ability of diarrheal calves,effectively regulate the imbalance of intestinal flora,and is beneficial to the body health of calves.关键词
初乳/腹泻/犊牛/免疫/肠道菌群Key words
colostrum/diarrhea/calf/immune/intestinal flora分类
农业科技引用本文复制引用
刘春雨,牛洁遥,何劲飞,刘锴,马德慧,薛江东..初乳对新生腹泻肉用犊牛免疫功能和直肠粪便菌群的影响[J].现代畜牧科技,2024,(9):31-34,4.基金项目
国家自然科学基金项目(31660726) （31660726）
内蒙古自治区肉牛疾病防控工程技术研究中心开放研究基金项目(MDK2018023) （MDK2018023）
