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影响前循环串联病变急诊血管内治疗预后的相关因素分析

刘岩 宁召腾 孙洪扬 于萍 王贤军

中风与神经疾病杂志2024,Vol.41Issue(9):776-781,6.
中风与神经疾病杂志2024,Vol.41Issue(9):776-781,6.DOI:10.19845/j.cnki.zfysjjbzz.2024.0149

影响前循环串联病变急诊血管内治疗预后的相关因素分析

Influencing factors for prognosis after emergency endovascular treatment of anterior circulation tandem lesions

刘岩 1宁召腾 2孙洪扬 3于萍 3王贤军3

作者信息

  • 1. 锦州医科大学,辽宁 锦州 121000
  • 2. 潍坊医学院临床医学院,山东 潍坊 261053
  • 3. 临沂市人民医院神经内科,山东 临沂 276000
  • 折叠

摘要

Abstract

Objective To investigate the efficacy of concurrent carotid artery stenting(CAS)in emergency endovascular treatment of anterior circulation tandem lesions and related influencing factors for prognosis.Methods A retrospective analysis was performed for the clinical data of 121 patients with anterior circulation tandem lesions who underwent emergency endovascular treatment in Linyi People's Hospital from January 2020 to December 2021,and intraoperative CT reperfusion injury was observed to decide whether concurrent CAS should be performed.The modified Rankin Scale(mRS)score on day 90 after surgery was used for evaluation,and then the patients were divided into good prognosis group(an mRS score of 0‒2)and poor prognosis group(an mRS score of 3‒6).The logistic regression analysis was used to investigate the influencing factors for the clinical prognosis of patients with anterior circulation tandem lesions after emergency endovascular treatment,including concurrent CAS.Results General clinical data were compared between the good prognosis group and the poor prognosis group,and the univariate analysis and multivariate binary logistic regression analysis showed that that preoperative CT ASPECTS score[odds ratio(OR)=1.207,95%confidence interval(CI)1.001‒1.456,P=0.049],time from disease onset to recanalization(OR=0.997,95%CI 0.995‒0.999,P=0.012),and symptomatic intracranial hemorrhage(OR=-3.057,95%CI 0.005‒0.411,P=0.006)were independent influencing factors for the prognosis of patients with anterior circulation tandem lesions after emergency endovascular treatment.Conclusion Exclusion of reperfusion injury based on intraoperative CT and concurrent CAS for anterior circulation tandem lesions do not increase the risk of hemorrhage,and presence of the risk of reperfusion injury based on intraoperative CT without stenting does not increase the risk of occlusion within a short period of time.There are no significant differences in 90-day good prognosis rate and mortality rate between the non-CAS group and the CAS group.High ASPECTS score is a protective factor for good prognosis in patients with anterior circulation tandem lesions,while a longer time from disease onset to recanalization and symptomatic intracranial hemorrhage are influencing factors for good prognosis.

关键词

串联病变/颈动脉支架植入/血管内治疗/预后

Key words

Tandem lesions/Carotid artery stenting/Endovascular treatment/Prognosis

分类

医药卫生

引用本文复制引用

刘岩,宁召腾,孙洪扬,于萍,王贤军..影响前循环串联病变急诊血管内治疗预后的相关因素分析[J].中风与神经疾病杂志,2024,41(9):776-781,6.

基金项目

临沂市重点研发计划(医药类)项目(2022YX0002) (医药类)

中风与神经疾病杂志

OACSTPCD

1003-2754

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