中国康复理论与实践2024，Vol.30Issue(9)：1074-1081,8.DOI:10.3969/j.issn.1006-9771.2024.09.011
健康人和脑卒中患者视觉反馈步行训练后脑激活特征的功能性近红外光谱技术研究
Characteristics of brain activation during treadmill walking with visual feedback in healthy subjects and hemiple-gic patients:a functional near infrared spectroscopy study
摘要
Abstract
Objective To compare the cortical activation characteristic in the healthy subjects and hemiplegia patients during execut-ing treadmill walking with visual feedback(TWVF). Methods From August to November,2021,eight stroke patients with right hemiplegia(patient group)and eight healthy subjects(healthy group)in Fifth Hospital of Xiamen were recruited.Both groups wore functional near-infrared spectroscopy(fNIRS)caps and executed TWVF,respectively.Experimental block design for walking modes in-cluded the preparation period(10 s)and task period(five cycles of"step 30 s-rest 30 s").The cortical activation(β values)were measured.The regions of interest(ROI)included the pre-motor cortex(PMC),supplementary motor area(SMA),primary motor cortex(M1),primary somatosensory cortex(S1)and sensorimotor cortex(SMC,M1+S1). Results No activation in bilateral M1,and some significant activation(P<0.05)in the left hemisphere SAM,PMC and S1,were found during walking in the healthy group.M1 was activated more in the unaffected(right)hemisphere than in the affected(left)hemisphere during walking in the patient group(P<0.05),and less PMC activation was found(P<0.05).M1 in bilateral hemispheres,SMA in the unaffected hemisphere and PMC in the affected hemi-sphere were activated more in the patient group than in the healthy group(P<0.05). Conclusion The locomotor network of SMC-PMC-SMA are activated more in the hemiplegic patients than in the healthy pepole during walking.M1 are almost not activated in the healthy people during walking,and compensa-torily activated in M1 of the unaffected side in the hemiplegic patients.关键词
脑卒中/步行/脑激活模式/功能性近红外光谱技术Key words
stroke/walking/brain activation/functional near infrared spectroscopy分类
医药卫生引用本文复制引用
谢丹丹,陈善佳,雷蕾,余果,余佳慧,赵嘉培,何晓阔..健康人和脑卒中患者视觉反馈步行训练后脑激活特征的功能性近红外光谱技术研究[J].中国康复理论与实践,2024,30(9):1074-1081,8.基金项目
1.厦门市医疗卫生重点项目(No.3502Z20234005) （No.3502Z20234005）
2.厦门市自然科学基金项目(No.3502Z202373135 （）
No.3502Z20227418) （）
3.福建省自然科学基金项目(No.2022D010) Xiamen Key Project of Medical Treatment and Public Health(No.3502Z20234005),Xiamen Natural Science Foundation(No.3502Z202373135 （No.2022D010）
No.3502Z20227418)and Fujian Province Natural Science Foundation(No.2022D010) （No.2022D010）
