首页|期刊导航|中国临床药理学杂志|成团泛菌感染患者的临床特征及菌株耐药性分析

成团泛菌感染患者的临床特征及菌株耐药性分析OA北大核心CSTPCD

Clinical characteristics and drug resistance analysis of Pantoea agglomerans infection

中文摘要英文摘要

目的 分析成团泛菌感染患者的临床特征及菌株的耐药性,为临床合理使用抗菌药物提供相应的参考依据.方法 分析成团泛菌感染患者的临床特征、治疗转归,以及成团泛菌的耐药性.结果 在22例成团泛菌感染患者中,男性16例(72.7%),女性6例(27.3%),60岁以上患者是主要感染人群(72.7%),11例患者合并引起免疫功能低下的基础疾病(50.0%).感染部位以肺部、泌尿系统及血液最为常见,59.1%为医院感染.成团泛菌对临床常用抗菌药物有很好的敏感性,哌拉西林/他唑巴坦、厄他培南、阿米卡星和头孢哌酮/舒巴坦敏感率为100.0%,左氧氟沙星敏感率为94.4%,头孢曲松敏感率为81.3%.结论 成团泛菌引起的感染多为院内感染,主要感染人群为老年人.虽然目前多数成团泛菌对临床常用抗菌药物敏感,但部分菌株已显示了多重耐药性.

Objective To analyze the clinical characteristics of patients infected with Pantoea agglomerans and the drug resistance of the strains,providing corresponding reference for the rational use of antibiotics in clinical practice.Methods The clinical characteristics,treatment outcomes of patients infected with Pantoea agglomerans,and the drug resistance of Pantoea agglomerans were analyzed.Results Among the 22 patients infected with Pantoea agglomerans,16 were male(72.7%),and 6 were female(27.3%).Patients over 60 years old were the main infected population(72.7%),and 11 patients had underlying diseases that caused low immune function(50.0%).Lung,urinary system,and blood were the most common sites of infection,and 59.1%were nosocomial infections.Pantoea agglomerans showed good sensitivity to commonly used clinical antibiotics.The sensitivity rates of piperacillin/tazobactam,ertapenem,amikacin,and cefoperazone/sulbactam were 100.0%,and the sensitivity rate of levofloxacin was 94.4%,and the sensitivity rate of ceftriaxone was 81.3%.Conclusion Infections caused by Pantoea agglomerans are mostly nosocomial infections,and the main infected population is the elderly.Although most Pantoea agglomerans are sensitive to commonly used clinical antibiotics,some strains have shown multiple drug resistance.

辛明明;马序竹;王小辉;林明贵

清华大学附属北京清华长庚医院/清华大学临床医学院感染性疾病科,北京 102218

药学

成团泛菌临床特征耐药性

Pantoea agglomeransclinical characteristicsdrug resistance

《中国临床药理学杂志》 2024 (019)

2763-2765 / 3

10.13699/j.cnki.1001-6821.2024.19.001

评论