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中国12省份重症医学科慢性危重症诊疗现状的调查报告OA北大核心CSTPCD

A survey report on the diagnosis and treatment status of chronic critical illness in intensive care units of 12 provinces in China

中文摘要英文摘要

目的 了解中国大陆重症医学科(ICU)内调查当日慢性危重症(CCI)临床诊疗现况.方法 以福建医科大学附属第二医院ICU为发起单位,通过微信向我国大陆地区12个省份的34家医院综合ICU从业2年以上医师发放问卷调查表,于2022-09-29当日填写并回收调查表,登记所有34家医院调查当日全部在床患者的病历资料.将患者分为CCI组和非CCI组,比较两组患者基本情况、主要诊断、主要合并症和并发症及治疗情况.结果 34家医院中,三级甲等医院22家(64.7%),三级乙等医院8家(23.5%),二级甲等医院4家(11.8%).共纳入409例ICU在床患者,其中CCI组110例(26.9%),非CCI组299例(73.1%).CCI组中包括气管切开或延长的机械通气70例(63.6%),脓毒症或者其他严重的感染51例(46.4%),多器官衰竭65例(59.1%),脑出血、脑缺血或颅脑外伤48例(43.6%),创伤24例(21.8%).与非CCI组比较,CCI组患者诊断脑卒中(31.8%)、肺炎(23.6%)、全身多发性骨折(9.1%)、腹腔感染(4.5%)和胰腺炎(3.6%)的比例,合并甲状腺功能减退症(8.2%)的比例,并发吸入性肺炎(18.2%)、多器官衰竭(59.1%,包括呼吸系统衰竭50.9%和中枢神经系统衰竭26.4%)、急性呼吸窘迫综合征(ARDS,23.6%)、耐药菌感染(58.2%,包括耐药阴性菌感染44.5%,耐药阳性菌感染9.1%和耐药真菌感染20.9%)、休克(42.7%,包括分布性休克30%)、脓毒症(36.4%,包括腹腔来源15.5%、胸腔和肺部来源14.5%以及血管导管来源5.5%的脓毒症)的比例以及携带经外周植入的中心静脉导管(PICC,6.4%)的比例均升高(P<0.05).在治疗方法上,CCI组患者行肠内营养(90.0%)、使用特殊级抗生素(32.7%)、行纤维支气管镜操作(40.9%)的比例均较高(P<0.05);CCI组患者吞咽功能体格检查评估比例(30.9%)、吞咽功能量表评估比例(18.2%)、神经肌肉电刺激使用率(24.5%)、功率自行车使用率(16.4%)、上肢训练比例(25.5%)、膈肌起搏器使用率(7.3%)高于非CCI组患者(P<0.05).结论 ICU内CCI患者发生率高,脑卒中、肺炎和全身多发骨折是前三位的主要诊断;CCI患者合并甲状腺功能减退症、并发吸入性肺炎和ARDS、多器官衰竭、耐药菌感染、休克和脓毒症的形势严峻.CCI患者特殊级抗生素应用和纤维支气管镜操作过多以及康复评定和治疗不足应该引起重视.

Objective To understand the current situation of clinical diagnosis and treatment of chronic critical illness(CCI)on the day of investigation in the Intensive Care Unit(ICU)in Chinese Mainland.Methods Starting from the ICU of the Second Affiliated Hospital of Fujian Medical University,a survey questionnaire was distributed through WeChat to physicians with more than 2 years of experience in the comprehensive ICU of 34 hospitals in 12 provinces of mainland China.The survey was completed and the questionnaires collected on September 29,2022,and all medical data of patients in all 34 hospitals on the day of the survey were recorded.All the patients were divided into CCI group and non-CCI group,and the basic information,main diagnosis,major comorbidities and complications,as well as treatment status of the two groups of patients were compared.Results Among the 34 hospitals,there were 22 tertiary Grade A hospitals(64.7%),8 tertiary Grade B hospitals(23.5%),and 4 secondary Grade A hospitals(11.8%).A total of 409 ICU patients were enrolled,including 110(26.9%)in the CCI group and 299(73.1%)in the non-CCI group.The CCI group included 70 cases(63.6%)of mechanical ventilation with tracheotomy or extension,51 cases(46.4%)of sepsis or other severe infection,65 cases(59.1%)of multiple organ failure,48 cases(43.6%)of cerebral hemorrhage,cerebral ischemia or traumatic brain injury,and 24 cases(21.8%)of trauma.Compared with the non-CCI group,the proportion of the patients with the following diagnosis in CCI group significantly increased(P<0.05),including stroke(31.8%),pneumonia(23.6%),multiple fractures(9.1%),abdominal infection(4.5%),pancreatitis(3.6%),combination with hypothyroidism(8.2%),concurrent aspiration pneumonia(18.2%),multiple organ failure(59.1%,including respiratory system failure 50.9%and central nervous system failure 26.4%),acute respiratory distress syndrome(ARDS,23.6%),drug-resistant bacterial infection(58.2%,including drug-resistant negative bacterial infection 44.5%,drug-resistant positive bacterial infection 9.1%,and drug-resistant fungal infection 20.9%),shock(42.7%,including distributed shock 30%),sepsis(36.4%,including abdominal origin 15.5%,chest and lung origin 14.5%and vascular catheter origin 5.5%),as well as central venous catheters with peripheral implantation(PICC,6.4%)(P<0.05).In terms of treatment methods,the proportion of patients in CCI group receiving enteral nutrition(90.0%),special grade antibiotics(32.7%),and fiberoptic bronchoscopy(40.9%)significantly increased(P<0.05).The swallowing function physical examination evaluation(30.9%),swallowing function scale evaluation(18.2%),the rate of using neuromuscular electrical stimulation(24.5%),the rate of using power cycling(16.4%),upper limb exercise(25.5%),and the rate of using diaphragmatic pacemaker(7.3%)in CCI group were significantly higher than those in non-CCI group(P<0.05).Conclusion The incidence of CCI in ICU patients is high,with stroke,pneumonia,and multiple fractures of the body being the top three main diagnoses.The situation is severe in CCI patients with hypothyroidism,concurrent aspiration pneumonia and ARDS,multiple organ failure,drug-resistant bacterial infection,shock,and sepsis.The excessive use of special grade antibiotics and fiberoptic bronchoscopy in CCI patients,as well as inadequate rehabilitation assessment and treatment,should be taken seriously.

郑雨馨;郑雪兰;锁叶;林凡森;施恩明;徐亮;刘玉琪

福建医科大学附属第二医院重症医学科福建省呼吸医学中心,福建泉州 362000武汉科技大学附属武昌医院重症医学科,湖北武汉 430060

临床医学

重症医学科慢性危重症康复

intensive care unitchronic critical illnessrehabilitation

《中国实用内科杂志》 2024 (009)

745-751 / 7

福建省卫健委创新课题(2020CXA046);福建省卫生健康中青年科研重大项目(2021ZQNZD008);武汉市中医药科研项目(WZ22C35)

10.19538/j.nk2024090105

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