基于CRITIC法麸、米、土炒山药质量评价模型的建立OACSTPCD

Objective:To investigate the relationship between physical parameters and active ingredients of stir-baked Dioscoreae Rhizoma with bran,rice and soil,and to establish a quality evaluation model for different processing of the medicinal.Methods:Dioscoreae Rhizoma was mixed evenly to prepare the decoction pieces.The physical parameters of the medicinal decoction pieces(relative density,water absorption,pH,oxidation value,color value)were determined.The contents of amylopectin and polysaccharide were determined by ultraviolet spectrophotometer.The contents of allantoin and 5-HMF were determined by high performance liquid chromatography(HPLC).The software SPSS25.0 was used to analyze the correlation of data and establish the regression model.The objective weight evaluation method of CRITIC was used to determine the weight coefficient of each chemical component index in different decoction pieces and establish the weight scoring model.Results:The analyzed results showed that the content of amylopectin in Dioscoreae Rhizoma was positively correlated with pH(P<0.05),allantoin was negatively correlated with the oxidation value and a∗ value of the decoction pieces(P<0.05),and the content of 5-HMF was significantly and positively correlated with the oxidation value and a∗value of the decoction pieces(P<0.05).The linear regression equation established between the weight scores and the water absorbance and L∗ values was:Y=27.308+122.214X(water absorption)+0.683X(L∗),R2=0.570;and the regression model between the weight scores and the content of amyloses and polysaccharides was Y=23.333+0.426X(amylose)+1.197X(polysaccharide),R2=0.753.Conclusion:There is a certain correlation between the physical parameters of the stir-baked Dioscoreae Rhizoma with bran,rice and soil and the active ingredients.According to the established regression model,the content of the active ingredients could be predicted by the relevant physical indicators;the overall quality of the Dioscoreae Rhizoma decoction pieces could be predicted by the analysis of water absorption,L∗ value,amylose and polysaccharide content.These can provide a certain reference basis for controlling the quality of stir-baked Dioscoreae Rhizoma with bran,rice and soil,in order to provide quality assurance for the clinical use of the medicinal.