眼针联合尾灸对脑卒中后认知功能障碍大鼠的影响与机制研究OA北大核心CSTPCD
Effect and mechanism of ophthalmic acupuncture combined with tail moxibustion in post-stroke cognitive impairment rats
目的 探讨眼针联合尾灸对脑卒中后认知功能障碍大鼠行为学、海马的影响和可能起效机制.方法 75只雄性SD大鼠采用随机数字表法分为假手术组(15只)和造模组(60只).造模组采用改良线栓法复制大脑中动脉闭塞模型,假手术组仅暴露右侧颈动脉.造模后通过Morris水迷宫实验筛选脑卒中后认知功能障碍大鼠48只,采用随机数字表法分为模型组、眼针组、尾灸组、眼针+尾灸组,每组12只.假手术组、模型组仅捆绑,不予任何干预;眼针组取双侧"肝区""肾区""心区""脾…查看全部>>
Objective To explore the effects and possible mechanisms of ophthalmic acupuncture combined with tail moxibustion on the behavior and hippocampus in rats with post-stroke cognitive impairment.Methods Seventy-five male SD rats were randomly divided into the sham operation group (15 rats) and the modeling group (60 rats) using the random number table method. A modified suture-occluded method was used to replicate the occlusion model of the middle cerebral arte…查看全部>>
唐鑫怡;张威;周鸿飞
辽宁中医药大学针灸推拿学院 沈阳 110847辽宁中医药大学附属医院辽宁中医药大学附属医院
中医学
眼针尾灸脑卒中后认知功能障碍氧化应激氧死亡大鼠
ophthalmic acupuncturetail moxibustionpost-stroke cognitive impairmentoxidative stressoxeiptosisrats
《北京中医药大学学报》 2024 (9)
1312-1321,10
国家自然科学基金项目(No.81703993)辽宁省应用基础研究计划项目(No.2023JH2/10130051)National Natural Science Foundation of China(No.81703993)
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