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一锅多组分反应选择性合成二芳基甲胺和三芳基甲烷

王一诺 王思然 赵奕龙 徐大振

大学化学2024,Vol.39Issue(8):324-330,7.
大学化学2024,Vol.39Issue(8):324-330,7.DOI:10.3866/PKU.DXHX202401063

一锅多组分反应选择性合成二芳基甲胺和三芳基甲烷

Selective Synthesis of Diarylmethyl Anilines and Triarylmethanes via Multicomponent Reactions:Introduce a Comprehensive Experiment of Organic Chemistry

王一诺 1王思然 1赵奕龙 1徐大振1

作者信息

  • 1. 南开大学化学学院,农药国家工程研究中心,天津 300071
  • 折叠

摘要

Abstract

This article presents a comprehensive organic chemistry experiment in which salicylaldehyde,phenylboronic acid,and aromatic amines are employed as the substrates.The selective synthesis of diarylmethyl aniline and triarylmethane could be achieved through the control of substituents.The structure of the product is characterized by 1H NMR and 13C NMR.This experiment combines theoretical knowledge to inspire students to think about mechanisms,helps them broaden their knowledge horizons,and establishes the concept of "green chemistry" and environmental awareness.

关键词

多组分反应/苯胺/苯硼酸/绿色化学

Key words

Multicomponent reactions/Aniline/Phenylboronic acid/Green chemistry

分类

社会科学

引用本文复制引用

王一诺,王思然,赵奕龙,徐大振..一锅多组分反应选择性合成二芳基甲胺和三芳基甲烷[J].大学化学,2024,39(8):324-330,7.

基金项目

国家级大学生创新创业训练计划(202310055078) (202310055078)

大学化学

1000-8438

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