腔镜与开放甲状腺癌颈侧区淋巴结清扫术临床疗效的Meta分析OACSTPCD

Objective:To compare the clinical effects and safety of endoscopic and open lateral neck dissection in papillary thy-roid carcinoma.Methods:A meta-analysis was made on the Chinese and English literature comparing endoscopy versus open surgery in lateral neck dissection for thyroid papillary carcinoma,related control studies published from Jan.2000 to Feb.2022 were enrolled.Stata 16.0 software was used for meta-analysis.Results:Seventeen studies involving a total of 1 442 patients were finally selected.Compared with the open group,the endoscopy group had longer operative time(WMD=22.74,95%CI=6.83～38.66,P<0.05),fewer number of positive lymph nodes(WMD=-0.47,95%CI=-0.76～-0.18,P<0.05),shorter postoperative hospital stay(WMD=-1.21,95%CI=-2.26～-0.16,P<0.05),lower pain score(WMD=-0.98,95%CI=-1.34～-0.63,P<0.05),lower incidence of complications(OR=-0.58,95%CI=-0.85～-0.31,P<0.05),smaller surgical scar(WMD=-7.9,95%CI=-8.51～-7.29,P<0.05),and higher cosmetic score(WMD=1.58,95%CI=0.62～2.54,P<0.05).Intraoperative blood loss,postoperative drainage volume,dissected lymph nodes did not differ significantly between the two groups(P>0.05).Conclusions:Endoscopic lateral neck dissection has the advantages of short hospital stay,light postoperative pain,few incidence of complications,and good aesthetics.In terms of tumor radical resection,the two sur-gical methods are comparable.Endoscopic lateral neck dissection is safe and feasible,and can be used as a treatment method for papillary thyroid carcinoma.