影像科学与光化学2024，Vol.42Issue(5)：512-520,9.DOI:10.7517/issn.1674-0475.2024.05.14
ACR TI-RADS 5类甲状腺结节患者的剪切波弹性成像杨氏模量最大值与结节钙化的关联
Association of Shear Wave Elastography Young's Modulus Maxima with Nodular Calcification in Patients with ACR TI-RADS Category 5 Thyroid Nodules
蔡芹芹 1刘辉 1高曼丽 1朱红岩 1荣亚洲1
作者信息
- 1. 宿迁市第一人民医院超声医学科,江苏宿迁 223800
- 折叠
摘要
Abstract
Objective:To investigate the correlation between shear wave elastography(SWE)Young's modulus maximum(Emax)and nodule calcification for patients with thyroid nodules from the American College of Radiology(ACR)Thyroid Imaging Report and Data Set(TI-RADS)in five categories of thyroid nodules.Methods:95 patients with ACR TI-RADS category 5 thyroid nodules seen in our hospital from January 2021 to January 2023 were selected for the study.The patients were divided into a group without nodular calcification(46 patients)and a group with nodular calcification(49 patients)according to whether they had nodular calcification.Independent risk factors for nodal calcification in patients with ACR TI-RADS category 5 thyroid nodules were screened using univariate and multivariate Logistic regression analysis,nomogram prediction models were constructed and the models were evaluated.The relationship between SWE Emax and nodal calcification in patients with ACR TI-RADS category 5 thyroid nodules was analysed by curve fitting.The correlation between SWE Emax and the degree of nodal calcification was analysed using the Spearman test.A receiver operator characteristic(ROC)curve was used to analyse the ability of SWE Emax to predict nodal calcification in patients with thyroid nodules.Results:Family history of calcified thyroid nodules,high density lipoprotein cholesterol(HDL-C),thyroid stimulating hormone(TSH),heavy taste,Emax,chronic adverse mood,and malignant nodules were independent risk factors for nodal calcification in patients with ACR TI-RADS category 5 thyroid nodules(P＜0.05).The application of smoothing curve fitting analysis revealed a positive correlation between SWE Emax and nodular calcification in ACR TI-RADS category 5 thyroid nodules.The Spearman test suggested a positive correlation between SWE Emax and nodal calcification in patients with ACR TI-RADS category 5 thyroid nodules,rs=0.830(P＜0.05).The ROC curve analysis demonstrated that the area under the curve(AUC)of Emax for predicting nodal calcification was 0.819(95％CI:0.776-0.891),the sensitivity and specificity were 81.64％and 82.61％respectively.The results of the evaluation of the nomogram model based on seven independent risk factors showed an AUC of 0.853(95％CI:0.785-0.937)and a C-index of 0.817,with the Hosmer-Lemeshow goodness-of-fit test suggesting a good fit(P=0.359)and a high net benefit value.Conclusion:Family history of thyroid nodular calcification,HDL-C,TSH,taste preference,Emax,long-term adverse mood,and malignant nodules were independent risk factors for nodular calcification in ACR TI-RADS category 5 thyroid nodules.There was an overall positive correlation between SWE Emax and the degree of nodular calcification in ACR TI-RADS category 5 thyroid nodules.关键词
甲状腺影像报告和数据系统/甲状腺结节/剪切波弹性成像/杨氏模量值/结节钙化Key words
TI-RADS/thyroid nodules/shear wave elastography/Young's modulus values/nodular calcification分类
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蔡芹芹,刘辉,高曼丽,朱红岩,荣亚洲..ACR TI-RADS 5类甲状腺结节患者的剪切波弹性成像杨氏模量最大值与结节钙化的关联[J].影像科学与光化学,2024,42(5):512-520,9.
