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Phenformin activates ER stress to promote autophagic cell death via NIBAN1 and DDIT4 in oral squamous cell carcinoma independent of AMPK

Dexuan Zhuang Jing Guo Xunwei Wu Shuangshuang Wang Huiting Deng Yuxin Shi Chang Liu Xue Leng Qun Zhang Fuxiang Bai Bin Zheng

国际口腔科学杂志（英文版）2024，Vol.16Issue(3)：471-485,15.
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国际口腔科学杂志（英文版）2024，Vol.16Issue(3)：471-485,15.DOI:10.1038/s41368-024-00297-w

Phenformin activates ER stress to promote autophagic cell death via NIBAN1 and DDIT4 in oral squamous cell carcinoma independent of AMPK

Phenformin activates ER stress to promote autophagic cell death via NIBAN1 and DDIT4 in oral squamous cell carcinoma independent of AMPK

Dexuan Zhuang 1Jing Guo 1Xunwei Wu 1Shuangshuang Wang 2Huiting Deng 3Yuxin Shi 3Chang Liu 2Xue Leng 2Qun Zhang 2Fuxiang Bai 2Bin Zheng4

作者信息

  • 1. School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University&Shandong Key Laboratory of Oral Tissue Regeneration&Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration&Shandong Provincial Clinical Research Center for Oral Diseases,Jinan,China||Engineering Laboratory for Biomaterials and Tissue Regeneration,Ningbo Stomatology Hospital,Savaid Stomatology School,Hangzhou Medical College,Ningbo,China
  • 2. School and Hospital of Stomatology,Cheeloo College of Medicine,Shandong University&Shandong Key Laboratory of Oral Tissue Regeneration&Shandong Engineering Research Center of Dental Materials and Oral Tissue Regeneration&Shandong Provincial Clinical Research Center for Oral Diseases,Jinan,China
  • 3. Engineering Laboratory for Biomaterials and Tissue Regeneration,Ningbo Stomatology Hospital,Savaid Stomatology School,Hangzhou Medical College,Ningbo,China
  • 4. Cedars-Sinai Cancer Institute,Department of Biomedical Sciences,Cedars-Sinai Medical Center,Los Angeles,CA,USA
  • 折叠

摘要

引用本文复制引用

Dexuan Zhuang,Jing Guo,Xunwei Wu,Shuangshuang Wang,Huiting Deng,Yuxin Shi,Chang Liu,Xue Leng,Qun Zhang,Fuxiang Bai,Bin Zheng..Phenformin activates ER stress to promote autophagic cell death via NIBAN1 and DDIT4 in oral squamous cell carcinoma independent of AMPK[J].国际口腔科学杂志（英文版）,2024,16(3):471-485,15.

基金项目

This study was supported by the National Natural Science Foundations of China(82273554,82073470)and the Shandong Provincial Key R&D Program(ZR2019ZD36). （82273554,82073470）

国际口腔科学杂志（英文版）

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