国际医学放射学杂志2024，Vol.47Issue(5)：610-613,4.DOI:10.19300/j.2024.L21328
原发性宫颈NK/T细胞淋巴瘤继发周围神经淋巴瘤病1例
Primary cervical NK/T-cell lymphoma with secondary peripheral nerve lymphomatosis:a case report
摘要
Abstract
Objective To explore the imaging characteristics of primary cervical NK/T-cell lymphoma(NKTCL)with secondary peripheral nerve lymphomatosis,improving understanding of the disease and providing a reference for diagnosis and treatment decision.Methods A retrospective analysis was conducted on the clinical data,CT,MRI,and 18F-FDG PET/CT imaging findings of a patient with primary cervical NKTCL over a 9-month treatment period.Relevant literatures were also reviewed.Results The patient was admitted to hospital with vaginal fluid as the first symptom.Pre-treatment CT examination showed that the cervix was significantly enlarged,showing an irregular soft tissue mass with a size of approximately 8.4 cmx6.8 cmx8.3 cm and a uniform density.MRI displayed the cervical mass as isointense on T1WI,hyperintense on FS-T2WI and DWI,and hypointense on the corresponding ADC map.Enhanced scans showed marked homogeneous enhancement of the lesion,involving the upper vaginal segment,with multiple lymph nodes seen adjacent to the bilateral iliac vessels.PET/CT showed increased metabolism in cervical masses and left para-iliac lymph nodes.During treatment,PET/CT showed a significant reduction in metabolic activity and size,and the treatment was evaluated as achieving complete remission.Post-treatment,secondary neurolymphomatosis developed.PET/CT showed new hypermetabolic lesions in the right nerve root at the C2/3 level of cervical spine and along the course of the left sciatic nerve in the thigh.A biopsy of the C2/3 cervical spine nerve root lesion confirmed NKTCL infiltration.Conclusions The typical imaging manifestations of primary cervical NKTCL include a large,metabolically active but homogeneous mass with intact cervical mucosa.Imaging examination plays an important role in pre-treatment evaluation,accurate staging,treatment efficacy assessment,recurrence monitoring,and guiding biopsy site selection.关键词
子宫肿瘤/NK/T细胞淋巴瘤/周围神经淋巴瘤病/体层摄影术,X线计算机/磁共振成像/正电子发射体层成像Key words
Uterine neoplasms/NK/T-cell lymphoma/Neurolymphomatosis/Tomography,X-ray computed/Magnetic resonance imaging/Positron emission tomography分类
医药卫生引用本文复制引用
庞丁华,肖国有,柴华..原发性宫颈NK/T细胞淋巴瘤继发周围神经淋巴瘤病1例[J].国际医学放射学杂志,2024,47(5):610-613,4.基金项目
广西科技计划项目(桂科AB19110015) （桂科AB19110015）
广西壮族自治区卫生健康委员会自筹经费科研课题(Z-A20230728) （Z-A20230728）
广西生物靶向诊治研究重点实验室开放课题(GXSWBX202203) （GXSWBX202203）
