河北医学2024，Vol.30Issue(9)：1555-1559,5.DOI:10.3969/j.issn.1006-6233.2024.09.027
术前白细胞衍生性指标对肝癌介入术后早期复发的预测价值研究
A Study on the Predictive Value of Preoperative Leukocyte Derivativeness Index for Early Recurrence after Hepatocellular Carcinoma Intervention
摘要
Abstract
Objective:To analyze the predictive value of preoperative leukocyte-derived indicators on early recurrence of liver cancer after interventional surgery.Methods:Totally 216 patients who underwent in-terventional surgery for liver cancer in the hospital were included in the study from January 2020 to January 2023.They were followed up for 1 year after surgery and were divided into a recurrence group(n=110)and a non-recurrence group(n=106)according to the recurrence status.Leukocyte-derived indicators of all study subjects were measured before surgery,including neutrophil-to-lymphocyte ratio(NLR),platelet-to-lymphocyte ratio(PLR),and lymphocyte-to-monocyte ratio(LMR).Subject operating characteristic curve(ROC)was performed to analyze the predictive value of preoperative levels of NLR,PLR,and LMR on early recurrence after interventional surgery for liver cancer.Results:The preoperative NLR and PLR levels in the recurrence group were higher than those in the non-recurrence group while the LMR level was lower than in the non-recurrence group(P<0.05).ROC curve analysis results showed that the area under the curve(AUC)of a combination of preoperative NLR,PLR,and LMR in predicting early recurrence after liver canc-er interventional surgery was 0.958,with a sensitivity of 82.73%and a specificity of 95.28%.The efficiency of combined prediction was better than that of each indicator(P<0.05).Conclusion:Preoperative leukocyte-derived indicators are closely related to early recurrence of liver cancer after interventional surgery.Preopera-tive measurement of NLR,PLR,and LMR levels can predict early recurrence after liver cancer interventional surgery,and provide a certain reference basis for guiding clinical treatment.关键词
肝癌介入术/中性粒细胞与淋巴细胞比值/血小板与淋巴细胞比值/淋巴细胞与单核细胞比值Key words
Hepatocellular carcinoma intervention/Neutrophil-to-lymphocyte ratio/Platelet-to-lymphocyte ratio/Lymphocyte-to-monocyte ratio引用本文复制引用
陈恕,吉九威,刘晓宇,冯立..术前白细胞衍生性指标对肝癌介入术后早期复发的预测价值研究[J].河北医学,2024,30(9):1555-1559,5.基金项目
2022年度自治区卫生健康科技计划项目,(编号:202202222) （编号:202202222）
内蒙古医科大学青年项目,(编号:YKD2022QN042) （编号:YKD2022QN042）
