结核与肺部疾病杂志2024，Vol.5Issue(5)：468-475,8.DOI:10.19983/j.issn.2096-8493.2024089
儿童哮喘起病年龄相关影响因素分析
Analysis of factors affecting the onset age of asthma in children
摘要
Abstract
Objective:This study aims to explore the factors influencing the age of onset in children with asthma.Methods:A retrospective study was conducted on 412 pediatric asthma patients(aged 0-18 years)treated at Ji'nan Children's Hospital between September 2020 and September 2022.Data were gathered through an asthma epidemiological questionnaire,which included information on basic demographics,age at first wheezing episode,age at asthma diagnosis,birth and feeding history,environmental factors,medical history,and family history of allergies.Multivariate logistic regression analysis was used to identify risk factors influencing the age of asthma onset in children.Results:The study included 412 children,of whom 208(50.5％)experienced asthma onset at or before the age of 3,while 204(49.5％)experienced onset after the age of 3.Multivariate logistic regression analysis identified several significant factors influencing the age of asthma onset:household smoking(OR=0.635,95％CI:0.411-0.983),cleaning the pillow core every 1-3 months(OR=2.352,95％CI:1.223-4.524),cleaning the pillow core every 3-6 months(OR=3.016,95％CI:1.244-7.310),predominantly meat-based diet(OR=0.427,95％CI:0.195-0.933),parity stage G2P2(OR=0.276,95％CI:0.151-0.507),parity stage G3P3 or higher(OR=0.357,95％CI:0.159-0.800),and having a father with asthma(OR=0.321,95％CI:0.118-0.875).Conclusion:This study identified household smoking,paternal asthma,frequency of pillow cleaning,parity stage,and dietary habits as significant factors influencing the onset age of childhood asthma,offering valuable insights for the prevention and early intervention of the disease.关键词
哮喘/儿童/发病年龄/因素分析,统计学Key words
Asthma/Child/Age of onset/Factor analysis,statistical分类
医药卫生引用本文复制引用
薛敏,魏小玲,刘苗,王静,张赟,马香..儿童哮喘起病年龄相关影响因素分析[J].结核与肺部疾病杂志,2024,5(5):468-475,8.基金项目
山东省儿童健康与疾病研究中心(SDPRC009) （SDPRC009）
济南市儿童呼吸病重点实验室 （）
山东省医药卫生重点项目(202306011027) （202306011027）
济南市临床科技创新项目(202225022 （）
202134067) （）
山东省自然科学基金面上项目(ZR2021MH147) （ZR2021MH147）
2023年济南市卫生健康委员会科技计划项目(2023-1-52) Shandong Provincial Clinical Research Center for Children's Health and Disease(SDPRC009) （2023-1-52）
Ji'nan Key Lab for Pediatric Respiratory Diseases （）
Shandong Province Medical and Health Key Projects(202306011027) （202306011027）
Clinical Science and Technology Innovation Plan in Ji'nan(202225022 （）
202134067) （）
Shandong Provincial Natural Science Program(ZR2021MH147) （ZR2021MH147）
2023 Ji'nan Municipal Health Commission Science and Technology Program Project(2023-1-52) （2023-1-52）
