解剖学杂志2024,Vol.47Issue(4):348-351,4.DOI:10.3969/j.issn.1001-1633.2024.04.013
同种异体带瓣管道的研究进展
Research progress on valved homograft conduits
摘要
Abstract
To treat complex valvular heart disease,cardiovascular conduits are necessary.These conduits can be made from artificial materials,valved homograft conduits(VHC),or valved xenograft conduits.VHC offer physiological advantages,including resistance to calcification and infection,and do not require lifelong anticoagulation,making them highly compatible with the human body.However,the shortage of donors and the inability to store VHC for a long time have impeded their widespread adoption.The cryopreservation technology is expected to solve this problem.This article reviews the progress in donor selection,preservation methods,and clinical applications of VHC,providing valuable insights for its reconstruction of left and right ventricular outflow tract in clinical use.关键词
同种异体带瓣管道/脱细胞/低温保存Key words
valved homograft conduits/decellularization/cryopreservation分类
医药卫生引用本文复制引用
刘子钰,杨斌,郭志坤..同种异体带瓣管道的研究进展[J].解剖学杂志,2024,47(4):348-351,4.基金项目
河南省科技攻关项目(LHGJ20220837) (LHGJ20220837)