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同种异体带瓣管道的研究进展

刘子钰 杨斌 郭志坤

解剖学杂志2024,Vol.47Issue(4):348-351,4.
解剖学杂志2024,Vol.47Issue(4):348-351,4.DOI:10.3969/j.issn.1001-1633.2024.04.013

同种异体带瓣管道的研究进展

Research progress on valved homograft conduits

刘子钰 1杨斌 2郭志坤3

作者信息

  • 1. 新乡医学院河南省医用组织再生重点实验室,新乡 453003||郑州第七人民医院心外科,郑州 453000
  • 2. 郑州第七人民医院心外科,郑州 453000
  • 3. 新乡医学院河南省医用组织再生重点实验室,新乡 453003
  • 折叠

摘要

Abstract

To treat complex valvular heart disease,cardiovascular conduits are necessary.These conduits can be made from artificial materials,valved homograft conduits(VHC),or valved xenograft conduits.VHC offer physiological advantages,including resistance to calcification and infection,and do not require lifelong anticoagulation,making them highly compatible with the human body.However,the shortage of donors and the inability to store VHC for a long time have impeded their widespread adoption.The cryopreservation technology is expected to solve this problem.This article reviews the progress in donor selection,preservation methods,and clinical applications of VHC,providing valuable insights for its reconstruction of left and right ventricular outflow tract in clinical use.

关键词

同种异体带瓣管道/脱细胞/低温保存

Key words

valved homograft conduits/decellularization/cryopreservation

分类

医药卫生

引用本文复制引用

刘子钰,杨斌,郭志坤..同种异体带瓣管道的研究进展[J].解剖学杂志,2024,47(4):348-351,4.

基金项目

河南省科技攻关项目(LHGJ20220837) (LHGJ20220837)

解剖学杂志

OACSTPCD

1001-1633

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