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多系统萎缩患者体位性低血压的危险因素分析

徐萱 王丽晔 张新宁 黄晶晶 王垚 薛静 赵倩煜 陈志刚

临床神经病学杂志2024,Vol.37Issue(5):330-335,6.
临床神经病学杂志2024,Vol.37Issue(5):330-335,6.

多系统萎缩患者体位性低血压的危险因素分析

Analysis of risk factors of orthostatic hypotension in patients with multiple system atrophy

徐萱 1王丽晔 2张新宁 3黄晶晶 1王垚 4薛静 5赵倩煜 6陈志刚2

作者信息

  • 1. 100029 北京中医药大学第二临床医学院
  • 2. 北京中医药大学东方医院脑病一科
  • 3. 西安市中医院脑病二科
  • 4. 清华大学工程物理系
  • 5. 北京市丰台中西医结合医院脑病科
  • 6. 北京中医药大学第三附属医院医务处
  • 折叠

摘要

Abstract

Objective To explore the risk factors of orthostatic hypotension(OH)in patients with multiple system atrophy(MSA).Methods A total of 199 MSA patients were included,and they were divided into groups based on the severity of OH.The data differences between the groups were compared,and the risk factors for the occurrence of OH in MSA patients were analyzed from ordered Logistic regression.Results There were significant differences in gender,diabetes,disease grade,syncope,supine hypertension,fatigue and brain protective drugs among patients with different OH grades(all P<0.05).Ordered Logistic regression analysis found that disease grade(probable MSA),syncope,supine hypertension,and fatigue were independent risk factors for the occurrence of OH in MSA patients(all P<0.05).Conclusions OH is commonly present in MSA patients,and its severity is influenced by many factors.Disease grade(probable MSA),syncope,lying hypertension and fatigue are independent risk factors of OH in patients with MSA.

关键词

多系统萎缩/体位性低血压/临床特征/危险因素

Key words

multiple system atrophy/orthostatic hypotension/clinical characteristics/risk factors

分类

医药卫生

引用本文复制引用

徐萱,王丽晔,张新宁,黄晶晶,王垚,薛静,赵倩煜,陈志刚..多系统萎缩患者体位性低血压的危险因素分析[J].临床神经病学杂志,2024,37(5):330-335,6.

基金项目

国家自然科学基金面上项目(8217152245) (8217152245)

首都卫生发展科研专项项目(首发2018-2-4202) (首发2018-2-4202)

北京中医药大学校级项目(2020-JYB-ZDGG-119) (2020-JYB-ZDGG-119)

临床神经病学杂志

OACSTPCD

1004-1648

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