临床肝胆病杂志2024，Vol.40Issue(10)：1954-1958,5.DOI:10.12449/JCH241005
代谢相关脂肪性肝病的发病机制与中医病机
Research advances in the pathogenesis of metabolic associated fatty liver disease
摘要
Abstract
Metabolic associated fatty liver disease(MAFLD)is currently the most common liver disease around the world.MAFLD may easily progress to the adverse outcomes such as hepatitis,liver fibrosis,and liver cirrhosis,and it is often accompanied by comorbidities such as diabetes,hypertension,hyperlipidemia,hyperuricemia,and cardiovascular and cerebrovascular diseases.Etiological treatment is the cornerstone of MAFLD treatment,and due to the complexity and adverse outcome of MAFLD,it is of great significance to explore the pathogenesis of MAFLD and develop effective prevention and treatment regimens and drugs.This article reviews the pathogenesis of MAFLD from the aspects of genetic factors,improper diet and oxidative stress,spleen-stomach damp-heat and insulin resistance,damp-heat and pathogenic Qi,organic acid metabolism,and intestinal microecology.关键词
非酒精性脂肪性肝病/脂类代谢/中医病因和病机Key words
Non-alcoholic Fatty Liver Disease/Lipid Metabolism/Etiological Factors and Pathogenesis(TCM)引用本文复制引用
姚树坤,刘婧,周天惠..代谢相关脂肪性肝病的发病机制与中医病机[J].临床肝胆病杂志,2024,40(10):1954-1958,5.基金项目
北京化工大学-中日友好医院生物医学转化工程研究中心联合基金项目(XK2022-07) Joint Fund Project of Biomedical Translational Engineering Research Center of Beijing University of Chemical Technology and China-Japan Friendship Hospital(XK2022-07) （XK2022-07）
