环境与职业医学2024，Vol.41Issue(9)：1025-1031,7.DOI:10.11836/JEOM24143
浙江省某市地铁氡浓度监测及其对相关工作人员染色体畸变和微核的影响
Radon concentration and related employees'chromosome aberration and micronuclei in sub-ways in a city of Zhejiang Province
摘要
Abstract
[Background]Excessive radon exposure is considered the second risk factor for lung cancer.Since the opening of the subway in a city of Zhejiang Province,the exposure level of radioactive gas radon in subway stations and its impact on occupational health have become one of the im-portant issues of public concern. [Objective]To monitor the radon concentration of subways in a city in Zhejiang Province and explore the effect of radon exposure on chromosome aberration and micronuclei in the working population. [Methods]A total of 55 vehicle control rooms of 55 stations affiliated to two different subway lines in a city were measured for one year;the 110 ticket offices and 55 security checkpoints from the same 55 stations were measured from 16 March to 14 June.The radon con-centrations were compared by job types,subway lines,and seasons referring to Measurement methods for determination of radon in en-vironmental air(HJ 1212-2021).Peripheral blood lymphocyte chromosome aberration and micronucleus analyses were conducted in 165 subway workers from monitoring sites for three different job types,then the influencing factors were analyzed.The detection methods were adopted from the standards of Test and assessment of chromosomal aberrations on occupational health examinations for radiation workers(GBZ/T 248-2014)and Standard for the method of micronucleus detection in lymphocytes on occupational health examination for radiation workers and exposure dose estimation(GBZ/T 328-2023). [Results]The radon concentration range of the target subways in Zhejiang Province was 10-320 Bq·m-3,all lower than the national limit(≤400 Bq·m-3).The differences in radon radioactivity levels among different lines,job types,and time segments were statistically significant(P<0.05).The rates of chromosomal aberration and micronucleus formation among the 165 subjects were 0.224%and 0.024%,respec-tively.There were significant differences in the rates of chromosome aberration and micronuclei among different jobs(vehicle control room,ticket office,security checkpoint)(P<0.05),but the abnormal rates were lower than the limits of the corresponding national stan-dard.No significant correlation was found between jobs and chromosomal aberrations or micronuclei(P>0.05).Chromosome aberration and micronuclei varied by age,subway station seniority,and smoking(P<0.05).No effect of the above factors on chromosome aberration and micronuclei was observed by logistic regression(P>0.05). [Conclusion]The radon concentration in the target subway system is at a normal level.The rates of chromosomal aberration and mi-cronucleus formation vary by jobs,but both are lower than the corresponding national limits.Therefore,radon exposure has not yet caused outstanding health impact on the subway workers.关键词
氡/地铁/监测/染色体畸变/微核/影响因素Key words
radon/subway/monitoring/chromosome aberration/micronuclei/influencing factor分类
医药卫生引用本文复制引用
宣志强,聂继华,黄芯瑜,赖忠俊,郭佳娣,郝小吉,俞顺飞,曹艺耀,王东航,张舵..浙江省某市地铁氡浓度监测及其对相关工作人员染色体畸变和微核的影响[J].环境与职业医学,2024,41(9):1025-1031,7.基金项目
浙江省医药卫生科学研究基金项目(2022KY133) This study was funded. （2022KY133）
