内蒙古民族大学学报（自然科学版）2024，Vol.39Issue(5)：27-33,7.DOI:10.14045/j.cnki.15-1220.2024.05.005
聚噻吩衍生物/银纳米线结合分子印迹法检测葡萄糖
Polythiophene Derivatives/Silver Nanowires Combined with Molecular Imprinting for Glucose Sensing
摘要
Abstract
A glucose biosensor was fabricated based on surface molecular imprinting(MIP)by depositing 3,4-ethylenedioxythiophene grafted with 3-fluorophenylboronic acid(EDOT-FPBA)and glucose onto silver nanowires.Specifically,silver nanowires(AgNWs),EDOT-FPBA,and glucose were sequentially deposited on the surface of a glassy carbon electrode(GCE).After eluting the glucose template,a molecularly imprinted glucose biosensor was obtained.Using electrochemical impedance spectroscopy,glucose detection was performed,revealing a linear rela-tionship between glucose concentration and charge transfer resistance within the range of 0.05 to 20.00 mmol/L,with a detection limit as low as 0.03 mmol/L(R2=0.990 5).Furthermore,the sensor exhibited excellent specificity,stabili-ty,reusability,and storage stability,allowing for sensitive detection of glucose at physiological pH levels.关键词
分子印迹法/葡萄糖检测/电化学/生物传感器/银纳米线Key words
molecular imprinting method/glucose detection/electrochemistry/biosensor/silver nanowires分类
化学化工引用本文复制引用
刘洋,李丽娟,陈志冉,白婷芳,乌兰格日乐,海文峰..聚噻吩衍生物/银纳米线结合分子印迹法检测葡萄糖[J].内蒙古民族大学学报（自然科学版）,2024,39(5):27-33,7.基金项目
国家自然科学基金项目(22164016) （22164016）
内蒙古自治区青年科技英才支持计划项目(NJYT23034) （NJYT23034）
内蒙古自治区自然科学基金项目(2024LHMS02019) （2024LHMS02019）
内蒙古自治区科技计划项目(2022YFSH0040) （2022YFSH0040）
内蒙古自治区高等学校科学技术重点研究项目(NJZZ21029) （NJZZ21029）
