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IGF2BP3在膀胱癌组织中的表达及临床意义分析

薛永豪 王磊 刘星达 刘鸿宇 王超奇

内蒙古民族大学学报(自然科学版)2024,Vol.39Issue(5):48-51,4.
内蒙古民族大学学报(自然科学版)2024,Vol.39Issue(5):48-51,4.DOI:10.14045/j.cnki.15-1220.2024.05.009

IGF2BP3在膀胱癌组织中的表达及临床意义分析

Analysis of the Expression and Clinical Significance of IGF2BP3 in Bladder Cancers

薛永豪 1王磊 1刘星达 1刘鸿宇 1王超奇2

作者信息

  • 1. 内蒙古民族大学临床医学院,内蒙古通辽 028000
  • 2. 内蒙古民族大学附属医院,内蒙古通辽 028000
  • 折叠

摘要

Abstract

To analyze the expression of insulin-like growth factor 2mRNA binding protein 3(IGF2BP3)in bladder cancer and its clinical significance.A total of 135 samples were collected,including 65 cases of bladder cancer and 70 cases of normal bladder tissue,the expression and clinical significance of IGF2BP3 in the two kinds of different samples were observed by immunohistochemistry.The results showed that in the two kinds of different samples,IGF2BP3 showed high expression levels in bladder cancer tissues,but almost no expression in normal bladders.Meanwhile,it was also found that the expression level of IGF2BP3 was positively correlated with patients'gender,smoking history,pathological grade and lymph node metastasis,but had no correlation with tumor stage.IGF2BP3 has a high value in the diagnosis of bladder cancer and in the assessment of tumor progression.

关键词

膀胱癌/IGF2BP3/免疫组化

Key words

bladder cancer/IGF2BP3/immunohistochemistry

分类

临床医学

引用本文复制引用

薛永豪,王磊,刘星达,刘鸿宇,王超奇..IGF2BP3在膀胱癌组织中的表达及临床意义分析[J].内蒙古民族大学学报(自然科学版),2024,39(5):48-51,4.

基金项目

内蒙古自治区自然科学基金面上项目(2021MS08071) (2021MS08071)

内蒙古自治区卫生和计划生育委员会医疗卫生科研计划项目(202202264) (202202264)

内蒙古自治区直属高校基本科研项目(GXKY23Z039) (GXKY23Z039)

内蒙古民族大学学报(自然科学版)

1671-0185

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