FUT6促进胃癌细胞增殖、侵袭及迁移OACSTPCD
FUT6 promotes the proliferation,invasion and migration of gastric cancer cells
目的 探究α1,3岩藻糖基转移酶-Ⅵ(FUT6)在胃癌中的表达及其对胃癌细胞增殖、侵袭及迁移的影响.方法 利用GEPIA网站、癌症基因组图谱(The Cancer Genome Atlas,TCGA)数据库分析FUT6在胃癌中表达情况,并分析其与肿瘤免疫的关系.通过Western blot检测胃癌细胞(MKN-45、MGC-803、BGC-823、SGC-7901、AGS)及胃黏膜上皮细胞(GES-1)中FUT6蛋白的表达水平,选取FUT6表达量…查看全部>>
Objective To investigate the expression of α1,3 fucosyltransferase-Ⅵ(FUT6)in gastric cancer and its effects on the pro-liferation,invasion and migration of gastric cancer cells.Methods GEPIA website and The Cancer Genome Atlas(TCGA)database were used to investigate the expression of FUT6 in gastric cancer and analyze its relationship with tumor immunity.The protein expres-sion level of FUT6 in gastric cancer cell lines(MKN-45,MGC-803,BGC-823,SGC-7901,AGS)and…查看全部>>
韩亚娟;王红梅;王强强;韩正全
蚌埠医科大学第一附属医院肿瘤内科,蚌埠 233000蚌埠市中医医院风湿免疫科蚌埠市中医医院风湿免疫科蚌埠医科大学第一附属医院肿瘤内科,蚌埠 233000
临床医学
胃癌FUT6上皮间质转化增殖侵袭迁移
gastric cancerFUT6epithelial-mesenchymal transitionproliferationinvasionmigration
《山西医科大学学报》 2024 (9)
1097-1104,8
蚌埠医学院自然科学重点项目(2021byzd040)
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