刑事技术2024，Vol.49Issue(5)：543-546,4.DOI:10.16467/j.1008-3650.2024.5020
一起强奸致孕案中葡萄胎的亲子鉴定分析
Analysis of Paternity Testing for Hydatidiform Mole in a Rape Case
薛天羽 1林锦锋 1周镭迪欧 2秦金风 3倪春雨3
作者信息
- 1. 宁波市公安司法鉴定中心,浙江 宁波 315016
- 2. 宁海县公安司法鉴定中心,浙江 宁海 315600
- 3. 海尔施基因科技股份有限公司,浙江 宁波 315042
- 折叠
摘要
Abstract
Hydatidiform mole(HM)is a kind of gestational trophoblastic disease caused by abnormal fertilization.The presence of abundant paternal genetic information plays a key role in the pathogenesis of hydatidiform mole.Paternity testing involving hydatidiform mole tissue is relatively rare in forensic practice.In the case discussed,the aborted tissue originating from a female victim under 14 at the time of her pregnancy was diagnosed with hydatidiform mole.It was morphologically consistent with hydatidiform mole,and showed typical genotyping features of a complete hydatidiform mole(CHM)fertilized by single sperm,i.e.homozygous in all 23 loci.The alleged suspect was not actually the biological father of the aborted embryonic tissue.The author consulted a large number of literatures to analyze the experimental results.Unexplained paternity incompatibility suggests a different biological father,who was finally found through comparison and retrieval in the DNA database.Further STR testing was performed using VeriFilerTM Plus kit,SureID® X37 kit and YfilerTM.Platinum Casework kit.One allele was detected in 23 autosome and 35 X chromosome STR loci from embryonic tissue,which was found in the genotype of the focused suspect.The STR typing technology could determine the type of hydatidiform mole and provide clues and evidence for the identification.This paper may provide enlightenment for the handling of similar cases.关键词
法医遗传学/DNA检验/亲子鉴定/葡萄胎Key words
forensic genetics/DNA examination/paternity testing/hydatidiform mole分类
社会科学引用本文复制引用
薛天羽,林锦锋,周镭迪欧,秦金风,倪春雨..一起强奸致孕案中葡萄胎的亲子鉴定分析[J].刑事技术,2024,49(5):543-546,4.
