临床医学工程2024,Vol.31Issue(10):1221-1222,2.DOI:10.3969/j.issn.1674-4659.2024.10.1221
胸腺法新辅助抗结核药物治疗对复治菌阳肺结核患者的影响
Impact of Therapy of Thymalfasin Assisted with Anti-Tuberculosis Drugs on Patients with Smear-Positive Retreatment Pul-monary Tuberculosis
马燕芳 1赖金梅 1廖观连1
作者信息
- 1. 龙岩市第二医院结核科,福建龙岩 364000
- 折叠
摘要
Abstract
Objective To analyze the effect of thymalfasin assisted with anti-tuberculosis drugs in the treatment of patients with smear-positive retreatment pulmonary tuberculosis(TB).Methods 116 patients with smear-positive retreatment TB were randomly divided into two groups.The control group was treated with anti-tuberculosis drugs,and the observation group was treated with anti-tuberculosis drugs+thymalfasin.The sputum negative conversion rate,lung function and immune function were compared between the two groups.Results After 2 months and 3 months of treatment,the sputum negative conversion rates of the observation group were higher than those of the control group(P<0.05).After treatment,FEV1,FEV1/FVC,FVC,CD4+,CD3+and CD4+/CD8+of the observation group were higher than those of the control group(P<0.05).Conclusions Thymalfasin assisted with anti-tuberculosis drugs in the treatment of smear-positive retreatment TB can increase the sputum negative conversion rate and improve the lung function and immune function of patients.关键词
胸腺法新/复治菌阳肺结核/肺功能/免疫功能Key words
Thymalfasin/Smear-positive retreatment pulmonary tuberculosis/Lung function/Immune function分类
医药卫生引用本文复制引用
马燕芳,赖金梅,廖观连..胸腺法新辅助抗结核药物治疗对复治菌阳肺结核患者的影响[J].临床医学工程,2024,31(10):1221-1222,2.