临床医学工程2024，Vol.31Issue(10)：1245-1246,2.DOI:10.3969/j.issn.1674-4659.2024.10.1245
不同剂量新活素在急诊PCI治疗急性心肌梗死中的效果与安全性
Effects and Safety of Different Doses of rhBNP in Emergency PCI for the Treatment of Acute Myocardial Infarction
刘钰 1卢士建 2王琛1
作者信息
- 1. 信阳市中心医院急诊内科,河南信阳 464000
- 2. 信阳市中心医院心内科,河南信阳 464000
- 折叠
摘要
Abstract
Objective To analyze the effects and safety of different doses of rhBNP in emergency percutaneous coronary intervention(PCI)for the treatment of acute myocardial infarction.Methods 64 patients with acute myocardial infarction were randomly divided into two groups.During emergency PCI treatment,group A was given 0.01 µg·kg-1·min-1 rhBNP,and group B was given 0.015 μg·kg-1·min-1 rhBNP for 24 h continuously.The therapeutic effect,vascular endothelial function and adverse reactions were compared between the two groups.Results No significant difference was found in the total effective rate and incidence of adverse reactions between the two groups(P＞0.05).After treatment,ET-1 in group B was significantly lower than that in group A,and NO was significantly higher than that in group A(P＜0.05).Conclusions High-dose rhBNP can obviously improve the clinical symptoms of patients with acute myocardial infarction treated by emergency PCI,and improve their vascular endothelial function,without increase of medication risk.关键词
新活素/急诊PCI/急性心肌梗死/血管内皮功能/疗效/安全性Key words
rhBNP/Emergency PCI/Acute myocardial infarction/Vascular endothelial function/Efficacy/Safety分类
医药卫生引用本文复制引用
刘钰,卢士建,王琛..不同剂量新活素在急诊PCI治疗急性心肌梗死中的效果与安全性[J].临床医学工程,2024,31(10):1245-1246,2.
