中国免疫学杂志2024,Vol.40Issue(10):2219-2222,2228,5.DOI:10.3969/j.issn.1000-484X.2024.10.034
单细胞转录组测序技术在自身免疫病中应用的最新研究进展
Latest research progress in application of single-cell transcriptome sequencing technology in autoimmune diseases
摘要
Abstract
Single-cell RNA sequencing technology takes a single cell as research object,counts and analyzes the gene expres-sion level of each transcript and heterogeneity between cells.This technology makes up for the defects of traditional sequencing techno-logy to some extent.Autoimmune disease is the damage or dysfunction of autotissue cells caused by autoimmune tolerance or abnormal regulation of autoimmunity cells.In this paper,the research results on application of single-cell RNA sequencing technology in autoim-mune disease in recent years are reviewed,which provides valuable clues for early realization of precise medical treatment.关键词
单细胞转录组测序/自身免疫病/研究进展Key words
Single-cell RNA sequencing/Autoimmune disease/Research progress分类
医药卫生引用本文复制引用
孙金梅,石春卫,杨桂连,杨文涛,王春凤..单细胞转录组测序技术在自身免疫病中应用的最新研究进展[J].中国免疫学杂志,2024,40(10):2219-2222,2228,5.基金项目
国家自然科学基金项目(32373023) (32373023)
吉林省科技发展计划项目(20210202102NC,20240101216JC) (20210202102NC,20240101216JC)
山东省重点研发计划项目(2022CXPT039). (2022CXPT039)