中国免疫学杂志2024，Vol.40Issue(10)：2236-2240,封3-封4,7.DOI:10.3969/j.issn.1000-484X.2024.10.037
靶向淋巴细胞治疗系统性红斑狼疮的研究进展
Latest research progress in lymphocyte-targeted treatment of systemic lupus erythematosus
摘要
Abstract
Systemic lupus erythematosus(SLE)is an autoimmune disease with high heterogeneity in tissues and organs,Whose pathogenesis is still unclear.Lymphocytes are important immune cells involved in the occurrence and development of SLE.It has been found that the abnormal activation of T cells and B cells are important causes of SLE.In this review,by summarizing the role of T cells and B cells in the pathogenesis of SLE and the latest research progress in lymphocyte-targeted treatment strategy of SLE,the important scientific evidences can be provided to the study of the pathogenesis of SLE and the development of new medicines for the treatment of SLE.关键词
系统性红斑狼疮/B细胞/T细胞/发病机制/单克隆自身抗体Key words
Systemic lupus erythematosus/B cells/T cells/Pathogenesis/Monoclonal autoantibody分类
社会科学引用本文复制引用
黄悦,洪金辉,杨穗碧,姜心怡,龚宇晴,吴静..靶向淋巴细胞治疗系统性红斑狼疮的研究进展[J].中国免疫学杂志,2024,40(10):2236-2240,封3-封4,7.基金项目
国家自然科学基金项目(81601428) （81601428）
浙江省自然科学基金项目(LY20H250001) （LY20H250001）
杭州师范大学科研启动基金项目(2019QDL017). （2019QDL017）
