中国医院用药评价与分析2024，Vol.24Issue(9)：1109-1112,4.DOI:10.14009/j.issn.1672-2124.2024.09.019
复方樟柳碱注射液治疗前部缺血性视神经病变的药品综合评价
Comprehensive Evaluation on Compound Anisodine Hydrobromide Injection in the Treatment of Anterior Ischemic Optic Neuropathy
摘要
Abstract
OBJECTIVE:To conduct a comprehensive drug evaluation on compound anisodine hydrobromide injection in the treatment of anterior ischaemic optic neuropathy,so as to provide evidence support for clinical medication decisions.METHODS:Related data were obtained by searching Chinese and English databases such as PubMed and CNKI,as well as drug manufacturers and market conditions.Comprehensive evaluation on compound anisodine hydrobromide injection in the treatment of anterior ischaemic optic neuropathy was conducted from six dimensions:effectiveness,safety,economical efficiency,innovativeness,appropriateness and accessibility.RESULTS:A total of 14 randomized controlled trials from 915 retrieved papers were finally enrolled.In terms of effectiveness,compared with the control drug,the therapeutic effective rate of compound anisodine hydrobromide injection was significantly higher,with statistically significant difference(P<0.05).In terms of safety,the difference in incidences of adverse drug reactions between compound anisodine hydrobromide injection and the control drug was not statistically significant(P>0.05).In terms of economical efficiency,compared with the control drug,the daily therapeutic cost of compound anisodine hydrobromide injection was 17.97 RMB,the cost was lower.Compound anisodine hydrobromide injection was national class Ⅲ new drugs,with no special requirements for application and high affordability.CONCLUSIONS:Compound anisodine hydrobromide injection has high clinical effective rate in the treatment of anterior ischaemic optic neuropathy,with low incidence of adverse drug reactions and a certain advantage in daily treatment cost.It is convenient for medical staffs to operate,covers a wide geographic area,and has good accessibility.关键词
复方樟柳碱注射液/前部缺血性视神经病变/药品综合评价Key words
Compound anisodine hydrobromide injection/Anterior ischemic optic neuropathy/Comprehensive drug evaluation分类
药学引用本文复制引用
冯英楠,邢晓璇,李晓曦,庄伟,王之舟,王可,张兰,董宪喆..复方樟柳碱注射液治疗前部缺血性视神经病变的药品综合评价[J].中国医院用药评价与分析,2024,24(9):1109-1112,4.基金项目
首都卫生发展科研专项(No.首发2024-2-2019) （No.首发2024-2-2019）
北京市医院管理中心"登峰"人才培养计划项目(No.DFL20190803) （No.DFL20190803）
中国科学技术协会科技智库青年人才计划项目(No.20220615ZZ07110070) （No.20220615ZZ07110070）
