中国中西医结合外科杂志2024，Vol.30Issue(5)：613-616,4.DOI:10.3969/j.issn.1007-6948.2024.05.001
阴茎交感神经皮肤反应评估养阴清热中药治疗阴虚火旺型早泄患者疗效的可行性研究
Feasibility study on evaluating the therapeutic effect of traditional Chinese medicine for nourishing Yin and clearing heat on premature ejaculation of Yin deficiency and hyperactive fire type based on penile sympathetic skin response
摘要
Abstract
Objective Exploring the clinical efficacy of traditional Chinese medicine for nourishing Yin and clearing heat(modified Zhibai Dihuang decoction)in the treatment of premature ejaculation patients with Yin deficiency and hyperactive fire,and the application value of penile sympathetic skin response(PSSR)evaluation in this regard.Methods 96 patients with primary premature ejaculation(PPE)of Yin deficiency and hyperactive fire type,in outpatient clinics were selected from January 2022 to Decembe 2023,randomly divided into two groups:the treatment group(traditional Chinese medicine for nourishing yin and clearing heat)and the control group(50 mg of sertraline hydrochloride tablets),with a treatment period of 8 weeks for both groups.Compare the intravaginal latency time(IELT),premature ejaculation diagnostic scale(PEDT),International Erectile Function Index-5(IIEF-5),and PSSR latency and amplitude detected by electromyography evoked potential before and after treatment.Results Before and after treatment,there was no statistically significant difference in IELT,PEDT,PSSR amplitude,and PSSR latency in the two groups(P＞0.05);After treatment,the incubation periods of IELT and PSSR in both groups were higher than before treatment,while the amplitudes of PEDT and PSSR were lower than before treatment,the difference is statistically significant(P＜0.05).There was no statistically significant difference in IIEF-5 between the two groups before and after treatment(P＞0.05).Conclusion Positive therapeutic effect of Traditional Chinese Medicine of nourishing yin and clearing heat in the treatment of primary premature ejaculation.The latent period of PSSR is a relatively objective evaluation index for evaluating the clinical efficacy of Traditional Chinese Medicine in the treatment of primary premature ejaculation.关键词
原发性早泄/盐酸舍曲林片/养阴清热中药/阴茎交感神经皮肤反应Key words
Primary premature ejaculation/sertraline/Yin deficiency and hyperactive fire/penile sympathetic skin response分类
医药卫生引用本文复制引用
陈敏慧,黄晓军,李哲扬,廖泽栋,黄文杰,赵寅,许科立..阴茎交感神经皮肤反应评估养阴清热中药治疗阴虚火旺型早泄患者疗效的可行性研究[J].中国中西医结合外科杂志,2024,30(5):613-616,4.基金项目
国家自然科学基金(82274258、81874400) （82274258、81874400）
