中国中医药信息杂志2024，Vol.31Issue(10)：191-196,封3,7.DOI:10.19879/j.cnki.1005-5304.202310100
中药干预Th17/Treg平衡治疗溃疡性结肠炎研究进展
Research Progress in Intervention of Chinese Materia Medica in Th17/Treg Balance in the Treatment of Ulcerative Colitis
摘要
Abstract
Pathological mechanism of ulcerative colitis(UC)is not fully clear,which may be the result of Th17/Treg immune imbalance and the interaction of multiple complex factors.Numerous studies have found that classical TCM prescriptions,experienced formulas and TCM active components could regulate Th17/Treg balance by intervening in cytokines,transcription factors,and signaling pathways,restore intestinal mucosal immune function,suppress intestinal mucosal inflammatory response,and repair intestinal mucosal barrier damage.Based on the research status of UC,Th17/Treg balance and TCM treatment,this article reviewed the relationship between Th17/Treg balance and UC,and explained the key role of Th17/Treg balance in the occurrence and development of UC.At the same time,the Chinese materia medica targeting to regulate the balance of Th17/Treg in the treatment of UC in recent years was summarized,in order to provide reference for the treatment of UC.关键词
溃疡性结肠炎/Th17/Treg平衡/作用机制/中药/综述Key words
ulcerative colitis/Th17/Treg balance/mechanism/Chinese materia medica/review分类
医药卫生引用本文复制引用
李开楊,黄财玉,赵琦,杨梅,黄敬,蔺晓源,刘杰民,唐云,郭震凡,石慧,杨月月..中药干预Th17/Treg平衡治疗溃疡性结肠炎研究进展[J].中国中医药信息杂志,2024,31(10):191-196,封3,7.基金项目
国家自然科学基金(82060850、82160866) （82060850、82160866）
贵州农村产业革命石斛专项资金项目(2020年) （2020年）
贵州省高等学校重点实验室(2023年) （2023年）
