不同水平斜视手术方式对黄斑区血流密度变化及FAZ面积的影响OACSTPCD

Objective To evaluate the changes of blood flow density(VD)and the area of no blood perfusion zone(FAZ)in the macular area after different levels of rectus muscle surgery using optical coherence tomography angiogra-phy.Method This study prospectively included 56 patients(112 eyes)who received horizontal strabismus surgery,inclu-ding group A(unoperated control group),group B(operated on one rectus muscle in one eye),group C(operated on two rectus muscles in one eye),group D(operated on only one external rectus muscle)and group F(operated on only one internal rectus muscle).Macular microvessels were evaluated with 3 ×3mm scanning mode centered on macular fovea before surgery,1 day after surgery,1 week after surgery and 1 month after surgery,and the changes of VD and FAZ of superficial capillary plexus were automatically analyzed.Result Compared with before surgery,the blood density in the temporal side was significantly increased 1 day after surgery(t=2.34,P=0.04).The SCP％of group C was(42.29±12.19)％,which was significantly higher than that of group A(41.38±11.49)％and group B(41.19±11.97)％,and the difference was statistically significant 1 day after surgery(P＜0.05).The temporal blood flow density(50.26±4.49)％of group C was significantly higher than that of group A(47.61±3.53)％and group B(48.22±3.29)％1 day after surgery and was also significantly higher than that of group C before surgery(48.27±3.23)％,the difference was statistically significant(P＜0.05).Conclusion Strabismus surgery may cause transient changes in retinal microcirculation in the early postoperative period,and the postoperative blood flow density increases significantly in patients with both rectus muscles in one eye,especially in the temporal region.