肿瘤药学2024,Vol.14Issue(4):429-435,7.DOI:10.3969/j.issn.2095-1264.2024.04.07
乳腺癌脑转移的药物治疗最新进展
Drug treatment advances for brain metastases of breast cancer
摘要
Abstract
With the progress of treatment,the survival time of patients with advanced breast cancer has been significant-ly extended,but the probability of central nervous system metastases in patients is also increased.Although local treatments such as surgery and radiation therapy are still the main means of brain metastases treatment,drug treatment of brain metas-tases has become the focus of research in recent years.In particular,anti-human epidermal growth factor receptor 2(HER2)drugs,such as small-molecule tyrosine kinase inhibitors,have shown good efficacy in the drug treatment of HER2-positive brain metastatic breast cancer.In addition,some studies have also shown that drugs acting on other targets,such as anti-an-giogenic drugs,PARP inhibitors,and immune checkpoint inhibitors,also have a certain effect on brain metastases.关键词
乳腺癌/脑转移/化疗/靶向治疗/免疫治疗Key words
Breast cancer/Brain metastasis/Chemotherapy/Targeted therapy/Immunotherapy分类
医药卫生引用本文复制引用
陈佳欣,王涛..乳腺癌脑转移的药物治疗最新进展[J].肿瘤药学,2024,14(4):429-435,7.基金项目
北京科创医学发展基金会(KC2022-ZZ-0091-7). (KC2022-ZZ-0091-7)