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基于"逆中枢化"理论探讨耳鸣的研究进展

惠渊 马祺 周学锐 高利娜 张甜 李妍怡 巩婷

中华耳科学杂志2024,Vol.22Issue(4):655-660,6.
中华耳科学杂志2024,Vol.22Issue(4):655-660,6.DOI:10.3969/j.issn.1672-2922.2024.04.025

基于"逆中枢化"理论探讨耳鸣的研究进展

Advances in Studies of Tinnitus from the Aspect of"Inverse Centralisation"

惠渊 1马祺 1周学锐 2高利娜 2张甜 2李妍怡 1巩婷1

作者信息

  • 1. 甘肃省中医院(兰州 730050)
  • 2. 甘肃中医药大学
  • 折叠

摘要

Abstract

In recent years,a large number of studies have aimed to further our understanding of tinnitus patho-genesis and clinical research.In this review,evidence of central gain associated with tinnitus and potential mechanisms are summarized from the aspect of the latest knowledge of neurobiological mechanisms.We propose that tinnitus may be a change caused by complex neuroplasticity,including neurophysiological changes in the disease process,modula-tion of different neurotransmitters and alteration of related regulatory genes.This is followed by a review on effective clinical treatments developed based on this theory,to provide new ideas for research and development of clinical treat-ments for tinnitus.

关键词

中枢化/耳鸣/研究进展

Key words

inverse centralization/tinnitus/research progress

引用本文复制引用

惠渊,马祺,周学锐,高利娜,张甜,李妍怡,巩婷..基于"逆中枢化"理论探讨耳鸣的研究进展[J].中华耳科学杂志,2024,22(4):655-660,6.

基金项目

联合科研基金一般项目(23JRRA1531) (23JRRA1531)

中华耳科学杂志

OA北大核心CSTPCD

1672-2922

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